Evaluation of ceruloplasmin in neonatal septicemia.

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dc.contributor.authorSuri, Men_US
dc.contributor.authorSharma, V Ken_US
dc.contributor.authorThirupuram, Sen_US
dc.date.accessioned1991-05-01en_US
dc.date.accessioned2009-05-27T06:00:40Z
dc.date.available1991-05-01en_US
dc.date.available2009-05-27T06:00:40Z
dc.date.issued1991-05-01en_US
dc.description.abstractSerial serum ceruloplasmin (Cp) levels were estimated in healthy and septicemic neonates, using single radial immunodiffusion. In 25 healthy neonates mean Cp levels were 19.82 mg/dl at birth, 18.20 mg/dl at 12-24 hours, 17.26 mg/dl at 14 +/- 4 days and 17.68 mg/dl at 28 +/- 4 days of life. For the entire neonatal period the mean Cp levels were computed to be 18.24 mg/dl. In 20 culture positive, septicemic neonates, mean Cp levels were 27 mg/dl at onset of disease, 28.65 mg/dl 12-24 hours later and 36.2 mg/dl after 7 +/- 3 days of start of illness (p less than 0.001 for all sampling intervals as compared to healthy group values in first month of life). The mean Cp levels were unaffected by gestational age in both groups. In the septicemic neonates, the mean Cp levels in dying neonates did not differ significantly from recovering neonates for all sampling intervals. It is concluded that estimation of serum Cp levels may help in diagnosis of neonatal septicemia, but it is not useful as an early diagnostic aid or for prognostication.en_US
dc.description.affiliationDepartment of Pediatrics and Microbiology, Maulana Azad Medical College, New Delhi.en_US
dc.identifier.citationSuri M, Sharma VK, Thirupuram S. Evaluation of ceruloplasmin in neonatal septicemia. Indian Pediatrics. 1991 May; 28(5): 489-93en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/14432
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshCeruloplasmin --analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunodiffusion --methodsen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfant, Premature, Diseases --blooden_US
dc.subject.meshKlebsiella Infections --blooden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshReference Valuesen_US
dc.subject.meshSepsis --blooden_US
dc.subject.meshStaphylococcal Infections --blooden_US
dc.subject.meshStaphylococcus aureusen_US
dc.subject.meshTime Factorsen_US
dc.titleEvaluation of ceruloplasmin in neonatal septicemia.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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