Palliative treatment of advanced non small cell lung cancer with weekly fraction radiotherapy.

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dc.contributor.authorBhatt, M Len_US
dc.contributor.authorMohani, B Ken_US
dc.contributor.authorKumar, Len_US
dc.contributor.authorChawla, Sen_US
dc.contributor.authorSharma, D Nen_US
dc.contributor.authorRath, G Ken_US
dc.date.accessioned2009-05-28T06:51:28Z
dc.date.available2009-05-28T06:51:28Z
dc.date.issued2000-12-23en_US
dc.description.abstractVarious hypofractionated radiotherapy schedules of radiotherapy have been tried in patients of advanced NSCLC with no conclusive superiority of either a more protracted low dose per fraction schedule or a rapid course of large fraction size. Present study evaluates the role of weekly high dose radiotherapy for the palliation of various intrathoracic symptoms like cough, chest pain, hemoptysis, dyspnoea. A total of 47 patients of advanced non-small cell lung cancer were treated with four weekly fraction of 5 Gy to a total dose of 20 Gy. Mean age at presentation was 53 years. Majority of patients had stage III disease. Pain relief was seen in 77% (23/30) patients with complete relief in 57%; haemoptysis was completely relieved in 77% patients (17/22); and cough was relieved in 68% (19/28) patients. Complete relief from dyspnoea was seen in only 5/12 (42%) patients whereas 2/12 (17%) patients had partial response. The present regime of 20 Gy in four weekly fractions was well tolerated by the patients without any identifiable acute toxicity and was simple and convenient to the patients, who traverse a long distance for radiotherapy in India. To conclude, weekly schedule af EBRT provide effective palliation of various intrathoracic symptoms in the patients with advanced NSCLC.en_US
dc.description.affiliationDepartment of Radiation Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.en_US
dc.identifier.citationBhatt ML, Mohani BK, Kumar L, Chawla S, Sharma DN, Rath GK. Palliative treatment of advanced non small cell lung cancer with weekly fraction radiotherapy. Indian Journal of Cancer. 2000 Dec; 37(4): 148-52en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/50483
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCarcinoma, Non-Small-Cell Lung --mortalityen_US
dc.subject.meshDose Fractionationen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLung Neoplasms --mortalityen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPalliative Care --methodsen_US
dc.subject.meshPrognosisen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshTreatment Outcomeen_US
dc.titlePalliative treatment of advanced non small cell lung cancer with weekly fraction radiotherapy.en_US
dc.typeJournal Articleen_US
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