Precocious Pseudopuberty due to Ovarian Causes.
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Date
2014-10
Journal Title
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Abstract
Background: It is important to differentiate central from peripheral causes of precocious
puberty because of distinct management options. Case Characteristics: 4 girls with
discordant pubertal development. Observations: All had low basal and GnRHa stimulated
FSH & LH level with high estradiol level. Abdominal ultrasonogram helped in diagnosing
precocious pseudopuberty- ovarian cyst in 3 children and juvenile granulosa cell tumour in
one. Outcome: Case 1 and 4 underwent surgery in view of persistent cyst and tumor,
respectively. Rest were managed conservatively. Regression of pubertal signs observed in
all children during follow-up. Conclusion: Precocious pseudopuberty can be differentiated
from central precocious puberty by GnRHa Stimulation test, bone age and abdominal
ultrasound.
Description
Keywords
GnRHa stimulation test, Juvenile granulosa cell tumor, Ovarian cyst
Citation
Dhivyalakshmi Jeevarathnam, Bhattacharyya Shaila, Reddy Rajeshwari, Arulselvi K I. Precocious Pseudopuberty due to Ovarian Causes. Indian Pediatrics. 2014 Oct; 51(10): 831-833.