Spectrum of non-fermenting gram negative bacilli isolated from patients with blood stream infections in a tertiary care hospital in North India

Simple item page
dc.contributor.authorNazir, Asifaen_US
dc.contributor.authorPeerzada, Bushra Yousufen_US
dc.contributor.authorSana, Ifshanaen_US
dc.date.accessioned2020-11-18T09:58:39Z
dc.date.available2020-11-18T09:58:39Z
dc.date.issued2019-05
dc.description.abstractBackground: Non-fermenting Gram-negative bacilli (NFGNB) are emerging as important causes of blood stream infections (BSI) and they are a major cause of morbidity and mortality worldwide. High intrinsic resistance of NFGNB to antimicrobial compounds makes the treatment of BSIs caused by them difficult and expensive. The aim of this study was to assess frequency and antibiotic susceptibility pattern of non-fermenting gram-negative rods isolated from blood culture of patients.Methods: A total of 3016 blood samples were received in the Department of Microbiology during the study period. All samples were processed according to standard microbiological procedures. Blood culture was done by automated blood culture system, (BacT/Alert) and identification and antibiotic susceptibility of non-fermenting gram negative bacilli was done by VITEK2 Compact System.Results: A total of 120 NFGNB were identified out of which the most common non-fermenters isolated were Acinetobacter sp. (95) followed by Pseudomonas aeruginosa (11), Burkholderia cepacia (09) Sternotrophomonas maltophilia (03) and Sphingomonas sp. (02). Most of the non -fermenters were multi drug resistant showing a high level of antibiotic resistance to most of the first- and second-line drugs. The most effective drugs were colistin and tigecycline.Conclusions: This study underlines the need to identify NFGNB in tertiary care hospitals and to monitor their susceptibility pattern to guide the clinician for better care and management of patients. Improved antibiotic stewardship and strict infection control measures especially hand washing need to be implemented to prevent emergence and spread of multidrug resistant NFGNB in health care settings.en_US
dc.identifier.affiliationsDepartment of Microbiology, Government Medical College, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.citationNazir Asifa, Peerzada Bushra Yousuf, Sana Ifshana. Spectrum of non-fermenting gram negative bacilli isolated from patients with blood stream infections in a tertiary care hospital in North India. International Journal of Research in Medical Sciences. 2019 May; 7(5): 1762-1766en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211472
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20191672en_US
dc.subjectAcinetobacter spen_US
dc.subjectAntibiotic susceptibilityen_US
dc.subjectNosocomial pathogensen_US
dc.subjectNon-fermentersen_US
dc.titleSpectrum of non-fermenting gram negative bacilli isolated from patients with blood stream infections in a tertiary care hospital in North Indiaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijrms2019v7n5p1762.pdf
Size:
239.75 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences