A study of relationship of hyperuricemia in hypothyroid patients

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dc.contributor.authorJat, Aen_US
dc.contributor.authorKhare, Aen_US
dc.contributor.authorPatel, Nen_US
dc.date.accessioned2020-09-24T07:54:00Z
dc.date.available2020-09-24T07:54:00Z
dc.date.issued2019-02
dc.description.abstractIntroduction: Hypothyroidism is a common metabolic disorder in general population. The prevalence of primary hypothyroidism is 1:100, but it may be 5:100 if patients with subclinical hypothyroidism (normal T4, raised TSH) are included.The degree of severity ranges from mild and unrecognized hypothyroid states to striking myxedema. The thyroid dysfunction increases with age, especially in women.Uric acid has been found to be significantly elevated in primary hypothyroidism in many studies. In comparison to the prevalence reported in the general population, a significant increase of both Hyperuricemia and gout was found in the hypothyroid patients. In hypothyroidism, the hyperuricemia is secondary to a decreased renal plasma flow and impaired glomerular filtrationThis study was designed for evaluation of uric acid levels in hypothyroid patients which might be helpful for clinical management of hypothyroid patients with hyperuricemia. Objective of Study: To find out any relationship between hyperuricemia in hypothyroidism patients. Methods:In our study, out of 100 patients, only 15 were found to have increased serum uric acid levels and only 3 had increased urinary uric acid levels. Out of these 15, 9 were females and 6 males, or can be said out of 70 females in study; only 9 were having increased serum uric acid levels. Results: In our study, the association between hypothyroid function and hyperuricemia seems to be week.No significant correlation was found betweenT3, T4 &TSH and serum uric acid. Conclusion: The correlation between hypothyroidism and gout still remains a matter of debate and more extensive studies need to be done to come to a definitive conclusion.en_US
dc.identifier.affiliationsAssistant Professor, Department of General Medicine; L.N. Medical College and Research Centre, Bhopal, MP, Indiaen_US
dc.identifier.affiliationsAssociate Professor, Department of General Medicine; L.N. Medical College and Research Centre, Bhopal, MP, Indiaen_US
dc.identifier.affiliationsProfessor, Department of General Medicine; L.N. Medical College and Research Centre, Bhopal, MP, Indiaen_US
dc.identifier.citationJat A, Khare A, Patel N. A study of relationship of hyperuricemia in hypothyroid patients. International Journal of Medical Research & Review. 2019 Feb; 7(1): 19-23en_US
dc.identifier.issn2320-8686
dc.identifier.issn2321-127X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/205272
dc.languageenen_US
dc.publisherSiddharth Health Research and Social Welfare Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume7en_US
dc.source.urihttps://ijmrr.medresearch.in/index.php/ijmrr/article/view/1030en_US
dc.subjectHypothyroidismen_US
dc.subjectUric Aricen_US
dc.subjectHyperuricemiaen_US
dc.titleA study of relationship of hyperuricemia in hypothyroid patientsen_US
dc.typeJournal Articleen_US
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