A comparative study of platelets behaviour in controls and acute myocardial infarction patients.

Simple item page
dc.contributor.authorDeshpande, N Jen_US
dc.contributor.authorRao, K Ren_US
dc.date.accessioned1998-04-04en_US
dc.date.accessioned2009-06-01T07:54:14Z
dc.date.available1998-04-04en_US
dc.date.available2009-06-01T07:54:14Z
dc.date.issued1998-04-04en_US
dc.description.abstractAcute myocardial infarction is one of the leading vascular diseases. Platelet-endothelium plays a crucial role in its etiopathogenesis. The present study was undertaken to compare the platelet aggregability in controls and acute myocardial infarction patients along with its effect on the peripheral platelet count. The work was conducted in five patients from ICCU and 5 controls between the age group of 40-60 years by using Chronolog Dual Channel Aggrometer with ADP and epinephrine as agonists. The platelets were counted by hemocytometry. The results were statistically analysed by Student's 't' test which was found to be significant. There was increase in the aggregation index in patients compared to controls. It was also observed that the degree of increase was more with ADP than epinephrine. Relatively, there was tendency of low platelet count. The increase in the aggregation index can be attributed to the hyperreactiveness of the platelets to ADP than epinephrine. The relative thrombocytopenia can be accounted to the sequestration of platelets in the coronary microvasculature. In conclusion, balance between EDRF and EDCF determines the platelet activation.en_US
dc.description.affiliationDepartment of Physiology, Government Medical College, Mysore.en_US
dc.identifier.citationDeshpande NJ, Rao KR. A comparative study of platelets behaviour in controls and acute myocardial infarction patients. Indian Journal of Physiology and Pharmacology. 1998 Apr; 42(2): 307-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108510
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAdulten_US
dc.subject.meshHumansen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyocardial Infarction --blooden_US
dc.subject.meshPlatelet Aggregation --physiologyen_US
dc.subject.meshPlatelet Counten_US
dc.titleA comparative study of platelets behaviour in controls and acute myocardial infarction patients.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Physiology and Pharmacology