Lipoprotein(a) as a risk factor for diabetic retinopathy in patients with type 2 diabetes mellitus.

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dc.contributor.authorChopra, Rupalien_US
dc.contributor.authorSaramma, Jaison Gen_US
dc.contributor.authorMary, Johnen_US
dc.contributor.authorRebecca, Abrahamen_US
dc.date.accessioned2007-05-26en_US
dc.date.accessioned2009-05-29T07:47:48Z
dc.date.available2007-05-26en_US
dc.date.available2009-05-29T07:47:48Z
dc.date.issued2007-05-26en_US
dc.description.abstractAIMS: To estimate serum lipoprotein(a) [Lp(a)] levels in patients with type 2 diabetes mellitus with and without diabetic retinopathy and to determine the correlation, if any, between serum Lp(a) levels and severity of diabetic retinopathy. MATERIALS AND METHODS: The study included a total of 200 patients of type 2 diabetes mellitus out of which 100 patients who had no retinopathy served as the control group and 100 patients with diabetic retinopathy formed the study group. A detailed fundus examination was done with dilated pupil. The Lp(a) levels were measured quantitatively in fasting venous samples by an immunoturbidimetric method using commercially available kits (Clonital). STATISTICAL ANALYSIS USED: Group comparisons involving qualitative measures were carried out using Chi square test. ANOVA procedure was applied for comparing group means. Logistic regression analysis was performed for independent factors associated with diabetic retinopathy. RESULTS: The average Lp(a) levels in the study group (68.5 mg/dl) were significantly higher than in the control group (25.1 mg/dl) (P 0.001). The Lp(a) levels were found to increase with increasing severity of diabetic retinopathy. CONCLUSIONS: Serum Lp(a) levels are significantly raised in patients with diabetic retinopathy as compared to those with no retinopathy.en_US
dc.description.affiliationDepartment of Ophthalmology, Christian Medical College and Hospital, Ludhiana, India. rupalichopra@gmail.comen_US
dc.identifier.citationChopra R, Saramma JG, Mary J, Rebecca A. Lipoprotein(a) as a risk factor for diabetic retinopathy in patients with type 2 diabetes mellitus. Indian Journal of Ophthalmology. 2007 May-Jun; 55(3): 195-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/69751
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.subject.meshAnalysis of Varianceen_US
dc.subject.meshApoprotein(a) --blooden_US
dc.subject.meshDiabetes Mellitus, Type 2 --blooden_US
dc.subject.meshDiabetic Retinopathy --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLogistic Modelsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.titleLipoprotein(a) as a risk factor for diabetic retinopathy in patients with type 2 diabetes mellitus.en_US
dc.typeJournal Articleen_US
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