Isolation of Mycobacterium tuberculosis from cerebrospinal fluid by the centrifugation & filtration methods.

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dc.contributor.authorSelvakumar, Nen_US
dc.contributor.authorVanajakumar,en_US
dc.contributor.authorThilothammal, Nen_US
dc.contributor.authorParamasivan, C Nen_US
dc.date.accessioned1996-05-01en_US
dc.date.accessioned2009-05-27T07:52:41Z
dc.date.available1996-05-01en_US
dc.date.available2009-05-27T07:52:41Z
dc.date.issued1996-05-01en_US
dc.description.abstractCerebrospinal fluid (CSF) samples were collected in 2 bottles each, from 112 children, examined clinically for tuberculous meningitis (TBM) One was processed by the centrifugation method and the other by the filtration method for the isolation of M. tuberculosis. Of these specimens, 11 and 13 yielded M. tuberculosis by the centrifugation method and the filtration method, respectively. In 7 specimens M. tuberculosis was isolated by both the methods; in 4, only by the centrifugation method, and in 6, only by the filtration method. Using both the methods, 17 (15.2%) of 112 specimens were culture positive for M. tuberculosis. The improvement in the rate of isolation, thus obtained, assumes importance as the confirmation of the diagnosis of TBM in all the clinically suspected cases is always desired. Moreover, the filtration method is simple and inexpensive and it can be carried out even in remote hospitals and the membranes, after filtration, can be transported to central mycobacteriology laboratory for culture of tubercle bacilli.en_US
dc.description.affiliationTuberculosis Research Centre (ICMR), Madras.en_US
dc.identifier.citationSelvakumar N, Vanajakumar , Thilothammal N, Paramasivan CN. Isolation of Mycobacterium tuberculosis from cerebrospinal fluid by the centrifugation & filtration methods. Indian Journal of Medical Research. 1996 May; 103(): 250-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/22413
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshBacteriological Techniquesen_US
dc.subject.meshCentrifugationen_US
dc.subject.meshCerebrospinal Fluid --microbiologyen_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFiltrationen_US
dc.subject.meshHumansen_US
dc.subject.meshMycobacterium tuberculosis --isolation & purificationen_US
dc.subject.meshTuberculosis, Meningeal --diagnosisen_US
dc.titleIsolation of Mycobacterium tuberculosis from cerebrospinal fluid by the centrifugation & filtration methods.en_US
dc.typeJournal Articleen_US
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