ROLE OF CYTOKINE STORM IN COVID-19 SEVERITY AND ITS TREATMENT MANAGEMENT

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dc.contributor.authorVerma, Shrikanten_US
dc.contributor.authorVerma, Sushmaen_US
dc.contributor.authorAfreen, Sheebaen_US
dc.contributor.authorAbbas, Mohammaden_US
dc.contributor.authorMahdi, Farzanaen_US
dc.date.accessioned2025-05-09T06:14:05Z
dc.date.available2025-05-09T06:14:05Z
dc.date.issued2024-07
dc.description.abstractThe human body has defense systems called the innate and adaptive immune systems. These systems include cells that produce substances called cytokines, like interleukins and interferons, to help the body respond to infections and other challenges. Normally, there's a mild stability among the body's inflammatory and anti-inflammatory responses, regulated by complex mechanisms. When this balance is disrupted, it can trigger a cascade of reactions leading to a massive release of cytokines. This can cause a self-amplifying cycle, leading to severe damage, organ failure, or even death. Disturbances can be triggered not only by infections but also by genetic conditions or certain medical treatments that affect the immune system. Understanding and treating these situations are challenging because of the intricate interactions within the immune systems. There's still much to learn, and effective treatments are limited at the moment.en_US
dc.identifier.affiliationsDepartment of Personalized and Molecular Medicine, Era University, Sarfarazganj, Lucknow, U.P., India-226003en_US
dc.identifier.affiliationsDepartment of Personalized and Molecular Medicine, Era University, Sarfarazganj, Lucknow, U.P., India-226003en_US
dc.identifier.affiliationsDepartment of Personalized and Molecular Medicine, Era University, Sarfarazganj, Lucknow, U.P., India-226003en_US
dc.identifier.affiliationsDepartment of Personalized and Molecular Medicine, Era University, Sarfarazganj, Lucknow, U.P., India-226003; Department of Microbiology, Era University, Sarfarazganj, Lucknow, U.P., India-226003en_US
dc.identifier.affiliationsDepartment of Personalized and Molecular Medicine, Era University, Sarfarazganj, Lucknow, U.P., India-226003en_US
dc.identifier.citationVerma Shrikant, Verma Sushma, Afreen Sheeba, Abbas Mohammad, Mahdi Farzana . ROLE OF CYTOKINE STORM IN COVID-19 SEVERITY AND ITS TREATMENT MANAGEMENT . Era's Journal of Medical Research. 2024 Jul; 11(1): 105-112en_US
dc.identifier.issn2348-9839
dc.identifier.issn2394-5222
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/242614
dc.languageenen_US
dc.publisherEra's Lucknow Medical College & Hospital, Lucknow in association with American University of Barbados (AUB)en_US
dc.relation.issuenumber1en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.24041/ejmr2024.16en_US
dc.subjectCytokine stormen_US
dc.subjectCOVID-19en_US
dc.subjectIL-6en_US
dc.subjectIL-1.en_US
dc.titleROLE OF CYTOKINE STORM IN COVID-19 SEVERITY AND ITS TREATMENT MANAGEMENTen_US
dc.typeJournal Articleen_US
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