Clinical correlation of vitamin D in depression

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dc.contributor.authorSharma, Nitinen_US
dc.contributor.authorBharti, Shantanuen_US
dc.contributor.authorJilani, Abdul Qadiren_US
dc.contributor.authorAgarwal, Anjuen_US
dc.contributor.authorSingh, Salonien_US
dc.contributor.authorSharma, Ruchitaen_US
dc.date.accessioned2020-04-09T07:42:26Z
dc.date.available2020-04-09T07:42:26Z
dc.date.issued2019-07
dc.description.abstractBackground: Literature has substantially advanced our understanding of the action of vitamin D in depression, much is still unknown concerning how vitamin D relates to dimensions of depression. Hence, authors aimed to examine the relationship of vitamin D in patients of depression, its correlation with the severity of depression and different symptom domains of depression.Methods: This Hospital based case control study included 75 patients with depression and 50 controls who were age and gender matched. Beck’s Depression Inventory II was used to assess the severity and symptom domains of depression. Vitamin D levels was assessed using Enhanced Chemiluminescence Technique.Results: Vitamin D deficiency was found significantly (<0.001*) among cases than controls. Significant (0.003*) inverse correlation was observed between severity of depression and vitamin D level.In cognitive symptoms, pessimism, punishment feeling, self-criticism, suicidal thoughts and worthlessness were found significantly higher among vitamin D deficient patients. However, in somatic-affective symptoms, crying, indecisiveness, loss of energy, irritability, concentration difficulty and being tired were the significant by prominent symptoms in vitamin D deficient patients.Conclusions: Vitamin D (<50 nmol/L) was found to be significantly associated with depressive symptoms with cognitive and somatic-affective symptoms being affected by vitamin D deficiency.en_US
dc.identifier.affiliationsDepartment of Psychiatry, Eras Lucknow Medical and Hospital, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.citationSharma Nitin, Bharti Shantanu, Jilani Abdul Qadir, Agarwal Anju, Singh Saloni, Sharma Ruchita. Clinical correlation of vitamin D in depression. International Journal of Advances in Medicine. 2019 Jul; 6(4): 1016-1020en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194366
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume6en_US
dc.subjectCognitive domainen_US
dc.subjectDepressionen_US
dc.subjectSomatic-affective domainen_US
dc.subjectVitamin Den_US
dc.titleClinical correlation of vitamin D in depressionen_US
dc.typeJournal Articleen_US
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