Danazol-induced Acute Pulmonary Fibrosis in a Patient with Idiopathic Thrombocytopenic Purpura: Could Anti Fibrosant Therapy be Useful?.

dc.contributor.authorFlores-Franco, René Agustín
dc.contributor.authorSalgado-Yáñez, Víctor Alejandro
dc.contributor.authorRivera-Olivas, Jesús
dc.contributor.authorRamos-Martínez, Ernesto
dc.date.accessioned2017-02-10T10:39:58Z
dc.date.available2017-02-10T10:39:58Z
dc.date.issued2016
dc.description.abstractIntroduction: Danazol is frequently used in the treatment of idiopathic thrombocytopenic purpura (ITP). Very occasionally are described in the elderly fatal respiratory complications related to this drug such as acute pulmonary fibrosis for which no treatment has proven to be effective. Presentation of Case: We describe a case of an old man with ITP treated with danazol who developed a pulmonary fibrosing disease not attributed to any other cause. Damaged lung reversed using an anti fibrosant therapy approved for other types of pulmonary fibrosing diseases. Discussion and Conclusion: Pulmonary fibrosing disease attributed to danazol is a condition refractory to systemic corticosteroids, but as shown in the present case, an anti fibrosant therapy has proven to be a useful alternative and could be recommended in the light of current knowledge.en_US
dc.identifier.citationFlores-Franco René Agustín, Salgado-Yáñez Víctor Alejandro, Rivera-Olivas Jesús, Ramos-Martínez Ernesto. Danazol-induced Acute Pulmonary Fibrosis in a Patient with Idiopathic Thrombocytopenic Purpura: Could Anti Fibrosant Therapy be Useful?. British Journal of Medicine and Medical Research. 2016; 16(12):1-4.en_US
dc.identifier.issn2231-0614
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183438
dc.language.isoenen_US
dc.source.urihttps://www.sciencedomain.org/abstract/15445en_US
dc.subjectIdiopathic thrombocytopenic purpuraen_US
dc.subjectdanazolen_US
dc.subjectlung fibrosisen_US
dc.subjectN-acetylcysteineen_US
dc.subjectpirfenidone.en_US
dc.titleDanazol-induced Acute Pulmonary Fibrosis in a Patient with Idiopathic Thrombocytopenic Purpura: Could Anti Fibrosant Therapy be Useful?.en_US
dc.typeArticleen_US
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