Antimicrobial and Antiinflammatory Potential of the Swedish Herbs Extract.

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dc.contributor.authorGomez-Flores, R
dc.contributor.authorGonzález-Meléndez, R
dc.contributor.authorCeballos-Salobreña, A
dc.contributor.authorTamez-Guerra, P
dc.contributor.authorTamez-Guerra, R
dc.contributor.authorRodríguez-Padilla, C
dc.contributor.authorMonreal-Cuevas, E
dc.contributor.authorGarza-Ramos, M A De La
dc.date.accessioned2015-10-07T05:08:05Z
dc.date.available2015-10-07T05:08:05Z
dc.date.issued2011-10
dc.description.abstractOral conditions that produce the greatest damage on individuals are cavities and periodontal disease, hence non-expensive and effective solutions are immediately required, particularly for communities with no access to dental services. The antimicrobial and anti-inflammatory potential of the Swedish bitter herbal extract was evaluated, using pure microbial cultures and clinical samples of 29 patients. It was observed that the extract caused significant (p<0.05) in vitro growth inhibition of up to 29%, 17%, 15%, and 50% against Prevotella intermedia, Bacteroides forsythus, Porphyromonas gingivalis and Streptococcus intermedius, respectively. In addition, the extract significantly (p<0.05) inhibited oral flora growth in patient samples showing MICs of < 7.8 μg/ml in 21% of the patients, 15.6μg/ml in 17% of the patients, 31.2 μg/ml in 10% of the patients, 62.5 μg/ml in 17% of the patients, 125 μg/ml in 3% of the patients, and 250 μg/ml in 7% of the patients, and induced a maximum of 75% growth inhibition, as measured by the MTT reduction assay. The extract was also observed to significantly suppress production of the inflammatory marker nitric oxide by LPS-treated murine peritoneal macrophages. The Swedish herbal extract may be considered in the clinics to prevent or treat bacterial oral infections and at the same time reducing inflammation.en_US
dc.identifier.citationGomez-Flores R, González-Meléndez R, Ceballos-Salobreña A, Tamez-Guerra P, Tamez-Guerra R, Rodríguez-Padilla C, Monreal-Cuevas E, Garza-Ramos M A De La. Antimicrobial and Antiinflammatory Potential of the Swedish Herbs Extract. European Journal of Medicinal Plants. 2011 Oct-Dec; 1(4): 107-117.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/163949
dc.language.isoenen_US
dc.source.urihttps://sciencedomain.org/abstract/178en_US
dc.subjectBacteriaen_US
dc.subjectinflammationen_US
dc.subjectmedicinal plantsen_US
dc.subjectoral infectionen_US
dc.subjectSwedish herbal extracten_US
dc.titleAntimicrobial and Antiinflammatory Potential of the Swedish Herbs Extract.en_US
dc.typeArticleen_US
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European Journal of Medicinal Plants