Coats’ disease of adult‑onset in 48 eyes.
| dc.contributor.author | Rishi, Ekta | |
| dc.contributor.author | Rishi, Pukhraj | |
| dc.contributor.author | Appukuttan, Bindu | |
| dc.contributor.author | Uparkar, Mahesh | |
| dc.contributor.author | Sharma, Tarun | |
| dc.contributor.author | Gopal, Lingam | |
| dc.date.accessioned | 2016-12-06T05:21:09Z | |
| dc.date.available | 2016-12-06T05:21:09Z | |
| dc.date.issued | 2016-07 | |
| dc.description.abstract | Background: Coats’ disease diagnosed in adulthood is an idiopathic, retinal exudative vascular disease without an inciting factor and has retinal features different from the childhood disease. Aim: To describe clinical features, treatment, and outcomes of eyes with Coats’ disease first diagnosed in patients 35 years or older. Materials and Methods: Retrospective chart review of patients first diagnosed with Coats’ disease at the age of 35 years or more at a tertiary eye care center between January 1995 and 2012. Eyes with retinal exudation or Coats’‑like response from secondary causes were excluded. Results: Forty‑five of 646 patients (7%) diagnosed with Coats’ disease had adult‑onset disease. Mean age at presentation was 47 years. Systemic hypertension was the most common (22%) systemic association and decreased vision the predominant presenting feature (83%). Localized (<6 clock h) presentation (74%) was unique to adults as against diffuse involvement (69%) in children (P < 0.001). Eyes were treated with laser photocoagulation 29 (60%), cryotherapy (4%), or both (2%) with surgical intervention in three (6%) eyes. Following treatment eight (35%) eyes improved, 11 (48%) eyes were stable while four (12%) eyes worsened due to complications. Conclusion: Adult‑onset Coats’ disease has less extensive involvement, more benign natural course, and a more favorable treatment outcome as against the childhood‑onset disease. The bilateral presentation emphasizes the need for regular follow‑up to detect possible future involvement of the fellow eye. | en_US |
| dc.identifier.citation | Rishi Ekta, Rishi Pukhraj, Appukuttan Bindu, Uparkar Mahesh, Sharma Tarun, Gopal Lingam. Coats’ disease of adult‑onset in 48 eyes. Indian Journal of Ophthalmology. 2016 July; 64(7): 518-523. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/179378 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026078/ | en_US |
| dc.subject | Adult | en_US |
| dc.subject | Coats’ disease | en_US |
| dc.subject | retina | en_US |
| dc.subject | retinal telangiectasia | en_US |
| dc.title | Coats’ disease of adult‑onset in 48 eyes. | en_US |
| dc.type | Article | en_US |