Study of relapse and failure cases of CAT I retreated with CAT II under RNTCP--an eleven year follow up.

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dc.contributor.authorMehra, R Ken_US
dc.contributor.authorDhingra, V Ken_US
dc.contributor.authorNish, Aggarwalen_US
dc.contributor.authorVashist, R Pen_US
dc.date.accessioned2008-10-20en_US
dc.date.accessioned2009-06-01T12:27:43Z
dc.date.available2008-10-20en_US
dc.date.available2009-06-01T12:27:43Z
dc.date.issued2008-10-20en_US
dc.description.abstractOBJECTIVE: To analyse the treatment outcome of Cat I smear positive relapse and failure cases and their fate when treated with Cat II regimen under RNTCP. METHODS: All Cat I smear positive relapse and failure TB patients treated with Category II regimen from 1994 to 2005 in a chest clinic of Delhi were analysed in this retrospective study. The re-treatment outcome data for relapse and failure cases of Cat I when treated with Cat II regimen was reviewed. RESULTS: The study population included 5576 registered as Cat I sputum positive cases in Gulabi Bagh chest clinic from 1994 to 2005. A total of 190 (3.4%) failed on Cat I regimen. Further out of 4905 (87.9%) successfully treated Cat I patients, 442 (9%) presented as relapses. The treatment success rate for relapse and failure cases of Cat I when subsequently treated with Cat II regimen were 76.4% and 48.8% respectively, with a significantly higher failure rate (27.6%) among Cat I failures subsequently treated with Cat II regimen. CONCLUSION: The failure cases of Cat I subsequently treated with Cat II were observed to have a significantly lower success rates (p < 0.05) as compared to relapse cases. The need for reappraisal of Cat II re-treatment regimen for failure cases among Cat I is suggested.en_US
dc.description.affiliationChest Clinic, Gulabi Bagh, Delhi.en_US
dc.identifier.citationMehra RK, Dhingra VK, Nish A, Vashist RP. Study of relapse and failure cases of CAT I retreated with CAT II under RNTCP--an eleven year follow up. Indian Journal of Tuberculosis. 2008 Oct; 55(4): 188-91en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/110567
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/ibr/ibrai.shtmlen_US
dc.subject.meshCommunicable Disease Control --methodsen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshRecurrenceen_US
dc.subject.meshRemission Inductionen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTime Factorsen_US
dc.subject.meshTreatment Failureen_US
dc.subject.meshTuberculosis --classificationen_US
dc.titleStudy of relapse and failure cases of CAT I retreated with CAT II under RNTCP--an eleven year follow up.en_US
dc.typeJournal Articleen_US
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