Analysis of Association of Brain Natriuretic Peptide Levels and Blood Pressure Variability

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dc.contributor.authorNachid, Men_US
dc.contributor.authorBenhar, Ien_US
dc.contributor.authorMounaouir, Ken_US
dc.contributor.authorEl-Jazouli, Aen_US
dc.contributor.authorGhali, Ben_US
dc.contributor.authorSalim, Aen_US
dc.contributor.authorDrighil, Aen_US
dc.contributor.authorHabbal, R.en_US
dc.date.accessioned2023-07-21T11:29:42Z
dc.date.available2023-07-21T11:29:42Z
dc.date.issued2023-05
dc.description.abstractObjective: The present study aimed to investigate the relationship between brain natriuretic peptide (BNP) levels and blood pressure variability among hypertensive patients aged over 40 years. Methods: The study recruited 120 patients from a cardiology outpatient clinic who had been diagnosed with hypertension and taking antihypertensive medication for at least 6 months. Demographic and clinical information, blood pressure measurements, and blood samples were collected to measure BNP levels. The standard deviation of the mean arterial pressure over 24 hours was calculated as a measure of blood pressure variability. Linear regression was used to examine the association between BNP levels and blood pressure variability while controlling for age, sex, BMI, and medication history. Results: The study found a significant positive association between BNP levels and blood pressure variability (?=0.31, p=0.002), even after controlling for other variables. The linear regression model explained 20% of the variance in blood pressure variability (R2=0.20, F=9.52, p<0.001). Conclusion: The findings suggest that higher BNP levels are associated with increased blood pressure variability among hypertensive patients. Further studies are needed to explore the underlying mechanisms and the potential implications of this association.en_US
dc.identifier.affiliationsCardiology Division , Ibn Rochd University Hospital , Casablanca 20250, Moroccoen_US
dc.identifier.citationNachid M, Benhar I, Mounaouir K, El-Jazouli A, Ghali B, Salim A, Drighil A, Habbal R.. Analysis of Association of Brain Natriuretic Peptide Levels and Blood Pressure Variability. Cardiology and Angiology: An International Journal. 2023 May; 12(4): 1-5en_US
dc.identifier.issn2347-520X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220322
dc.languageenen_US
dc.publisherSciencedomain Internationalen_US
dc.relation.issuenumber4en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.9734/ca/2023/v12i4337en_US
dc.subjectBrain natriuretic peptideen_US
dc.subjectblood pressure variabilityen_US
dc.subjecthypertensionen_US
dc.subjectantihypertensive medicationen_US
dc.subjectlinear regression.en_US
dc.titleAnalysis of Association of Brain Natriuretic Peptide Levels and Blood Pressure Variabilityen_US
dc.typeJournal Articleen_US
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