Ketoconazole in the treatment of Cushing's disease.

Simple item page
dc.contributor.authorDash, R Jen_US
dc.contributor.authorKhandekar, Sen_US
dc.contributor.authorLata, Ven_US
dc.contributor.authorBhansali, Aen_US
dc.date.accessioned1990-07-01en_US
dc.date.accessioned2009-05-30T23:54:55Z
dc.date.available1990-07-01en_US
dc.date.available2009-05-30T23:54:55Z
dc.date.issued1990-07-01en_US
dc.description.abstractSix patients with Cushing's disease received ketoconazole for 7-10 weeks following ketoconazole challenge test. Clinical and hormonal alterations in circulating cortisol, 17 OH progesterone, androstenedione and testosterone were assessed during the therapy. There was significant clinical improvement which corresponded to a fall in cortisol, androstenedione and testosterone. The rise in 17 OH progesterone and the fall in cortisol suggest a blockade at 17,20 desmolase and 11 B-hydroxylase in the cortisol bio-synthetic pathway.en_US
dc.description.affiliationDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh.en_US
dc.identifier.citationDash RJ, Khandekar S, Lata V, Bhansali A. Ketoconazole in the treatment of Cushing's disease. Journal of the Association of Physicians of India. 1990 Jul; 38(7): 486-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/90846
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.mesh17-alpha-Hydroxyprogesteroneen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAndrostenedione --blooden_US
dc.subject.meshCushing Syndrome --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHydrocortisone --blooden_US
dc.subject.meshHydroxyprogesterones --blooden_US
dc.subject.meshKetoconazole --administration & dosageen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTestosterone --blooden_US
dc.subject.meshTime Factorsen_US
dc.titleKetoconazole in the treatment of Cushing's disease.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of the Association of Physicians of India