Hospital-based study on demographic, hematological, and biochemical profile of lung cancer patients

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dc.contributor.authorGaur, Priyankaen_US
dc.contributor.authorBhattacharya, Sandeepen_US
dc.contributor.authorKant, Suryaen_US
dc.contributor.authorKushwaha, RA S.en_US
dc.contributor.authorGarg, Rajiven_US
dc.contributor.authorPandey, Sarikaen_US
dc.contributor.authorDubey, Abhisheken_US
dc.date.accessioned2020-11-18T10:08:10Z
dc.date.available2020-11-18T10:08:10Z
dc.date.issued2020-09
dc.description.abstractBackground: Lung cancer is considered as the most commonly diagnosed cancer. It is the leading cause of cancer-related mortality. Smoking and environmental pollutants act as important risk factors in majority of lung cancer cases (80%–90%). Material and Methods: This is a hospital-based study carried on in lung cancer patients of North India. Demographic profile of lung cancer patients was recorded. Hematological and biochemical profiles of lung cancer patients and healthy controls were compared. Results: Highest proportion of lung cancer was found in the age group of 46–60 years. Lung cancer was seen in highest number in male gender (76.63%) and also in those patients belonging to the rural category (84.58%). In this study, only 3.98% lung cancer patients having the past history of cancer and 5.47% showing the family history of cancer. Significant differences were found in weight and body mass index (BMI) of lung cancer patients when compared to healthy control (P < 0.0001). Hemoglobin (Hb) was found lower in lung cancer patients as compared with healthy controls. Significant difference was also observed in Hb levels of these two groups (P < 0.000). The serum protein level was lower in lung cancer patients than healthy controls. A significant difference was also observed in the protein levels of these two groups (P < 0.0001). Serum alkaline phosphatase (ALP) levels were higher in lung cancer patients in comparison to healthy controls. A significant difference was also observed in serum ALP levels in lung cancer patients as compared with healthy controls (P < 0.0001). Conclusions: Significant difference between BMI, Hb, serum albumin, and total protein was found in this study. These biomarkers may be helpful in the diagnosis of lung cancer at early stage and also in the follow-up assessment of the effects of treatmenten_US
dc.identifier.affiliationsDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.citationGaur Priyanka, Bhattacharya Sandeep, Kant Surya, Kushwaha RA S., Garg Rajiv, Pandey Sarika, Dubey Abhishek. Hospital-based study on demographic, hematological, and biochemical profile of lung cancer patients. Journal of Cancer Research and Therapeutics. 2020 Sep; 16(4): 839-842en_US
dc.identifier.issn0973-1482
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/213712
dc.languageenen_US
dc.publisherWolters Kluwer India Pvt. Ltd.en_US
dc.relation.issuenumber4en_US
dc.relation.volume16en_US
dc.source.urihttps://dx.doi.org//10.4103/jcrt.JCRT_185_18en_US
dc.titleHospital-based study on demographic, hematological, and biochemical profile of lung cancer patientsen_US
dc.typeJournal Articleen_US
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