Evaluation of standardisation parameters, pharmacognostic study, preliminary phytochemical screening and in vitro antidiabetic activity of Coccinia indica fruits as per WHO guidelines.
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Date
2014-07
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Abstract
Coccinia indica an annual creeper is available all over India and well known for its
antidiabetic property. In the present investigation, aqueous extract, and ethanolic extract of
the fruits were made using hot extraction procedure using soxhlet apparatus, decoction and
maceration. The qualitative phyto-chemical screening procedure was performed on each
extract. Phyto-chemical study reveals that carbohydrates, tannins, phenols, alkaloids, saponins
was present in both the extracts. An attempt has been made to highlight this folk herbal
medicine through present study which will assist in the identification of fresh as well as dried
crude samples of fruits anatomically and physiochemically. TLC finger printing and
fluorescence analysis of powdered fruits has been conducted and reported .The antidiabetic
activity is conducted by enzyme inhibition (α-glycosidase) in invitro method on each extract
and ethanolic extract showed significant inhibition.
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Keywords
Coccinia indica, Antidiabetic, α-glycosidase
Citation
Alagar Raja M, Sushma K, David Banji1, Rao KNV, Selvakumar D. Evaluation of standardisation parameters, pharmacognostic study, preliminary phytochemical screening and in vitro antidiabetic activity of Coccinia indica fruits as per WHO guidelines. Indian Journal of Pharmaceutical & Biological Research. 2014 Jul-Sept ; 2 (3): 54-64.