Role of haematological parameters in oral potentially malignant disorders and oral squamous cell carcinoma-A comparative study

dc.contributor.authorP, Preethien_US
dc.contributor.authorN.D.V.N, Shyamen_US
dc.contributor.authorN, Vaishalien_US
dc.contributor.authorR, Poornimaen_US
dc.contributor.authorR, Shravanien_US
dc.contributor.authorM, Priyankaen_US
dc.date.accessioned2019-12-02T09:49:13Z
dc.date.available2019-12-02T09:49:13Z
dc.date.issued2018-06
dc.description.abstractContext Oral squamous cell carcinoma (OSCC) is one of the most common cancers in human population and has a multifactorial aetiology. It is often preceded by oral potentially Malignant Disorders (OPMDs). Studies have shown that OSCC and OPMDs cause significant variations in various haematological parameters. Aim and objectives To assess the role of haematological parameters like haemoglobin, erythrocyte sedimentation rate, red blood cell count, white blood cell count and differential leukocyte count in OPMDs and OSCC and also to compare these parameters among OPMDs, OSCC and controls. Materials and methods Study comprises 30 diagnosed cases each of OPMDs and OSCC and 10 normal healthy age and sex-related individuals. Blood sample was collected from the patients and was evaluated for various haematological parameters by Sahli's acid haematin method, Westergren method and Coulter Counter ZF-6. Results There was a statistically significant difference in haemoglobin, red blood cell count, erythrocyte sedimentation rate, differential leukocyte count between OSCC, OPMDs and controls. Conclusion In the present study, haematological parameters were significantly altered in OPMDs and OSCC, and these variations may be useful in the prediction of malignant transformation and prognosis.en_US
dc.identifier.affiliationsPost Graduates, Department of Oral Pathology, Government Dental College and Hospital, Afzal Gunj, Hyderabad, 500012, Telangana, Indiaen_US
dc.identifier.affiliationsProfessor and HOD, Department of Oral Pathology, Government Dental College and Hospital, Afzal Gunj, Hyderabad, 500012, Telangana, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Oral Pathology, Government Dental College and Hospital, Afzal Gunj, Hyderabad, 500012, Telangana, Indiaen_US
dc.identifier.citationP. Preethi, N.D.V.N. Shyam, N. Vaishali, R. Poornima, R. Shravani, M. Priyanka. Role of haematological parameters in oral potentially malignant disorders and oral squamous cell carcinoma-A comparative study. Indian Journal of Mednodent and Allied Sciences. 2018 Jun; 6(2): 59-65en_US
dc.identifier.issn2347-6192
dc.identifier.issn2347-6206
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/186108
dc.languageenen_US
dc.publisherAssociation of Medical Dental and Allied Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.5958/2347-6206.2018.00009.2en_US
dc.subjectDifferential leukocyte counten_US
dc.subjectWBC counten_US
dc.subjectErythrocyte sedimentation rateen_US
dc.subjectHaemoglobinen_US
dc.subjectOral potentially malignant disordersen_US
dc.subjectOral squamous cell carcinomaen_US
dc.titleRole of haematological parameters in oral potentially malignant disorders and oral squamous cell carcinoma-A comparative studyen_US
dc.typeJournal Articleen_US
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