Study of prevalence and types of anemia in primary hypothyroidism

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dc.contributor.authorYadav, Rakesh K.en_US
dc.contributor.authorAhmad, Mansooren_US
dc.contributor.authorMathur, Manoj K.en_US
dc.contributor.authorDhingra, Vishalen_US
dc.date.accessioned2020-04-09T07:42:53Z
dc.date.available2020-04-09T07:42:53Z
dc.date.issued2019-09
dc.description.abstractBackground: Hypothyroidism is common disease with varying frequency between countries. Anemia in hypothyroidism can be normocytic normochromic, microcytic hypochromic and macrocytic hypochromic. Anemia severity is associated with hypothyroidism degree. Objective of this study to study the association between anemia and hypothyroidism and prevalence and types of anemia in primary hypothyroidism (subclinical and overt both).Methods: This cross sectional study was carried out at tertiary care hospital in North India. Newly diagnosed 100 primary hypothyroid patients and 100 controls with age and sex matched evaluated for anemia. Prevalence and types of anemia were studied and severity of anemia was correlated with that of hypothyroidism.Results: Anemia was observed in 90 patients with hypothyroidism. Symptoms due to anemia were higher in cases than in controls. RBCs morphology showed normocytic normochromic in 59, microcytic hypochromic in 26 and macrocytic hypochromic in 15 cases. Serum anti-TPO positivity was present in 71.1% in cases as compared to 33.33% in controls. Anemia was severe in cases with high TSH.Conclusions: Anemia was more prevalent in cases of hypothyroidism than in euthyroid controls. Normocytic normochromic type of anemia was most common type in this study. Serum anti-TPO positivity was 71.1% in cases. There was statistically significant negative correlation between TSH and haemoglobin. Symptoms of anemia were more in hypothyroid patients than in euthyroid anemic patients.en_US
dc.identifier.affiliationsDepartment of Medicine, M.L.N. Medical College (Allahabad) Prayagraj, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, M.L.N. Medical College (Allahabad) Prayagraj, Uttar Pradesh, Indiaen_US
dc.identifier.citationYadav Rakesh K., Ahmad Mansoor, Mathur Manoj K., Dhingra Vishal. Study of prevalence and types of anemia in primary hypothyroidism. International Journal of Advances in Medicine. 2019 Sep; 6(5): 1580-1583en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194465
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20194221en_US
dc.subjectAnemiaen_US
dc.subjectAnti-TPOen_US
dc.subjectPrimary hypothyroiden_US
dc.subjectTSHen_US
dc.titleStudy of prevalence and types of anemia in primary hypothyroidismen_US
dc.typeJournal Articleen_US
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