Alteration of Pulmonary Venous Flow Doppler Post Transcatheter Closure of Atrial Septal Defect

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dc.contributor.authorGobran, S. M. Aen_US
dc.contributor.authorEl-Saied, A. Men_US
dc.contributor.authorEl-Shedoudy, S. A. Aen_US
dc.contributor.authorMaria, D. A.en_US
dc.date.accessioned2023-07-21T11:29:25Z
dc.date.available2023-07-21T11:29:25Z
dc.date.issued2022-10
dc.description.abstractBackground: Atrial septal defect is a common congenital heart anomaly results in hemodynamically significant right ventriclular volume overload and an increase in the pulmonary venous flow. Aim: Evaluate changes of pulmonary venous flow parameters after transcatheter closure of secundum atrial septal defect. Patients and Methods: 50 patients with atrial septal defect aged from 3.5 to 31 years were included in the study. Pulmonary venous flow Doppler and right ventricular function were evaluated before and after successful transcatheter closure by transthoracic and transesophageal echocardiography. Results: The defect size ranged from 15 to 37mm with a mean (24.96 ±7.52), Normal systolic and diastolic waves of pulmonary venous flow Doppler were replaced by a continuous antegrade wave (mean 60±13.6 cm/s) in all atrial septal defect patients. Post-closure, the normal pulmonary venous flow pattern was regained, two separate waves, with a significant decrease in mean peak Systolic wave velocity (44.54±8.12 cm/sec vs 69.61±12.37, P=0.000), the mean peak Diastolic Wave velocity (55.85±9.81 cm/sec vs 72.65±10.38, P=0.000) and a significant increase in the mean peak atrial reversal wave velocity (28.75±4.63cm/sec vs 21.18±3.64, P=0.000). In multivariate regression analysis, significant predictors of haemodynamic significant ASD were ASD size,(odds ratio 1.508, P=0.007, 95% CI 1.153,2.671) and ASD/IAS ratio (odds ratio 2.313, P=0.001, 95% CI 1.064,3.104). Conclusions: Atrial septal defect patients have characteristic pulmonary venous flow pattern: continuous antegrade wave with systolic predominance and decrease in atrial reversal wave, which return to normal after closure. These changes could be helpful echocardiographic tool in prediction of successful closure of the defect.en_US
dc.identifier.affiliationsCardiology Department, Faculty of Medicine, Tanta University, Egypt.en_US
dc.identifier.citationGobran S. M. A, El-Saied A. M, El-Shedoudy S. A. A, Maria D. A.. Alteration of Pulmonary Venous Flow Doppler Post Transcatheter Closure of Atrial Septal Defect. Cardiology and Angiology: An International Journal. 2022 Oct; 11(4): 376-383en_US
dc.identifier.issn2347-520X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220276
dc.languageenen_US
dc.publisherSciencedomain Internationalen_US
dc.relation.issuenumber4en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.9734/ca/2022/v11i4292en_US
dc.subjectAtrial Septal Defect Secundum Type (ASDII)en_US
dc.subjectPulmonary Venous Flow (PVF)en_US
dc.subjectPulmonary Artery Pressure (PAP)en_US
dc.titleAlteration of Pulmonary Venous Flow Doppler Post Transcatheter Closure of Atrial Septal Defecten_US
dc.typeJournal Articleen_US
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