Six-Minute Walk Test Outcomes in Patients with Diffuse Parenchymal Lung Disease

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dc.contributor.authorRana, Srijnaen_US
dc.contributor.authorMahajan, Sandeepen_US
dc.contributor.authorKajal, NCen_US
dc.contributor.authorGupta, Sandeepen_US
dc.contributor.authorVohra, Shekharen_US
dc.contributor.authorSugandha, Swatien_US
dc.contributor.authorKaur, Amritpalen_US
dc.contributor.authorRandhawa, Dilbagen_US
dc.contributor.authorNeki, NSen_US
dc.date.accessioned2020-01-02T06:08:25Z
dc.date.available2020-01-02T06:08:25Z
dc.date.issued2019-07
dc.description.abstractThe 6-minute walk test (6MWT) is used to measure exercise capacity and assess prognosis in diffuse parenchymal lung disease (DPLD). Although the 6MWT is usually considered to be a test of submaximal exercise capacity in DPLD, the physiological load imposed by this test is not well described and 6MWT outcomes are poorly understood. This study aimed to compare cardiorespiratory responses to 6MWT in people with DPLD. Methods: An observational crosssectional study was carried out in a single tertiary care center in northern India which included 50 consecutive subjects (age >12 years) who had diffuse parenchymal lung diseases. In this study, the clinical, radiological and histological data subjects was collected. 6MWT was done of all the patients and results tabulated. Result: Desaturation on 6MWT (SPo2 <88% or fall of 4% from baseline) were seen in total of 33(66%) patients with most cases being IPF in which 17 patients (89.47%) out 19 cases showed desaturation. This was followed by NSIP with 4(67%) of of 6 cases and CTD-ILD having 7(53.8%) out of 13 cases showed desaturation. More studies are required from developing countries to ascertain the spectrum of DPLDs in different geographic. Conclusion: On average, the 6MWT elicits a high but submaximal oxygen uptake in people with DPLD. Fibrosis is associated with maximum destauration in 6MWT. However the physiological load varies between individuals, with higher peak VO2 in those with more severe disease that may match or exceed that achieved on CPET. The 6MWT is not always a test of submaximal exercise capacity in people with DPLD.en_US
dc.identifier.affiliationsJunior Resident, Chest and TB department, Government Medical College, Amritsar, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Chest and TB Department, Government Medical College, Amritsar, Indiaen_US
dc.identifier.affiliationsProfessor, Chest and TB Department, Government Medical College, Amritsar, Indiaen_US
dc.identifier.affiliationsAssistant professor, Department of Medicine, Maharishi Markandeshwar Medical College And Hospital Kumarhatti, Solan , Indiaen_US
dc.identifier.affiliationsSenior Resident. Department of Obs & Gynae, Maharishi Markandeshwar Medical College And Hospital Kumarhatti, Solan , Indiaen_US
dc.identifier.affiliationsProfessor, Medicine Department, Government Medical College, Amritsar, India.en_US
dc.identifier.citationRana Srijna, Mahajan Sandeep, Kajal NC, Gupta Sandeep, Vohra Shekhar, Sugandha Swati, Kaur Amritpal, Randhawa Dilbag, Neki NS. Six-Minute Walk Test Outcomes in Patients with Diffuse Parenchymal Lung Disease. Annals of International medical and Dental Research. 2019 Jul; 5(4): 4-6en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/188915
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber4en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2019.5.4.TB2en_US
dc.subjectExercise testen_US
dc.subjectpulmonary fibrosisen_US
dc.subjectDiffuse parenchymal lung diseaseen_US
dc.titleSix-Minute Walk Test Outcomes in Patients with Diffuse Parenchymal Lung Diseaseen_US
dc.typeJournal Articleen_US
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