Accuracy of 64-slice coronary CT angiography in predicting percentage diameter stenosis.

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dc.contributor.authorHarish, Aen_US
dc.contributor.authorKhatri, Payalen_US
dc.contributor.authorPriyadarshini, Hen_US
dc.contributor.authorSelvakumar, Sen_US
dc.contributor.authorArunkumar, Nen_US
dc.contributor.authorSivakumar, Aen_US
dc.contributor.authorEzhilan, Jen_US
dc.contributor.authorMullasari, Ajit Sen_US
dc.date.accessioned2008-07-27en_US
dc.date.accessioned2009-05-27T04:28:50Z
dc.date.available2008-07-27en_US
dc.date.available2009-05-27T04:28:50Z
dc.date.issued2008-07-27en_US
dc.description.abstractOBJECTIVE: Aim of our study was to evaluate the diagnostic accuracy of 64-slice CT coronary angiogram in measuring the percentage diameter stenosis compared to invasive angiography. METHODS AND RESULTS: 100 consecutive patients with more than 50% stenosis in at least one major coronary artery measured by 64-slice CT angiogram were included in the study. Patients with atrial fibrillation, history of allergy to contrast agent, acute coronary syndrome, renal insufficiency, history of previous coronary bypass surgery or percutaneous transluminal coronary stent, heart rate more than 70 per minute at the time of scan in spite of beta-blocker therapy, and calcium score >2000 Agaston units were not included in the study. 15-segment American Heart Association classification was used, and segments were compared using qualitative angiography. 192 segments (12.80%) could not be assessed due to poor image quality. The major cause for poor image quality was dense calcification precluding the luminal assessment (60.42%). Comparing the maximal percentage diameter stenosis by 64-slice CT versus invasive angiogram, the Spearman correlation coefficient between the two modalities was 0.788 and p value was <0.001. Bland-Altman analysis showed a mean difference in percentage stenosis of 2.1 +/- 16.22%. A total of 91.97% (401 of 436) of segments were within 1.96 standard deviations. CONCLUSION: This study shows that 64-slice CT coronary angiogram is accurate in detecting percentage diameter stenosis compared to coronary angiogram if the image quality is good. Calcifications and motion artifacts are the main culprits of poor image quality.en_US
dc.description.affiliationDepartment of Cardiology, Institute of Cardio-Vascular Diseases, Madras Medical Mission, Mugappair, Chennai, India. dr_harisha@rediffmail.comen_US
dc.identifier.citationHarish A, Khatri P, Priyadarshini H, Selvakumar S, Arunkumar N, Sivakumar A, Ezhilan J, Mullasari AS. Accuracy of 64-slice coronary CT angiography in predicting percentage diameter stenosis. Indian Heart Journal. 2008 Jul-Aug; 60(4): 296-301en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/5734
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshCoronary Angiographyen_US
dc.subject.meshCoronary Restenosis --diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshStatistics, Nonparametricen_US
dc.subject.meshTomography, X-Ray Computeden_US
dc.titleAccuracy of 64-slice coronary CT angiography in predicting percentage diameter stenosis.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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