Assessment of ST Segment Resolution as a Predictor of Outcome in Acute Myocardial Infarction after Thrombolysis

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dc.contributor.authorMandal, Ranjanaen_US
dc.contributor.authorYadav, Kiranen_US
dc.date.accessioned2020-09-24T07:10:28Z
dc.date.available2020-09-24T07:10:28Z
dc.date.issued2019-08
dc.description.abstractIntroduction: Coronary heart disease (CHD) is a major causeof mortality and morbidity all over the world. This study wasundertaken to assess the resolution of ST segment at 90 min ofthrombolysis in STsegment elevation myocardial infarction asa predictor of short term outcome in terms of adverse eventsand mortality during hospital stay.Material and methods: A total of 100 patients with firstepisode of ST elevation myocardial infarction without anyconventional contraindication for thrombolysis were takenfor the study. % of ST segment resolution after 90 minof thrombolysis was calculated and correlation with vitalparameters like Killip class, ejection fraction, incidence ofarrhythmias, prognosis in the patients with acute MyocardialInfarction.Results: Out of 100 patients who were thrombolysed, 30%had failed thrombolysis. Patient who presented within 6hours of chest pain had 7.7% failed thrombolysis which wassignificantly lower than patients who presented >6 hrs ofchest pain with 44.5% failure rate, p value 0.0002. Failure ofthrombolysis was higher in Diabetic patient (p value= 0.02)and hypertensive patient (p value= <0.0001). Risk factorslike diabetes, hypertension significantly affect the outcomeof thrombolysis. Mortality was seen in 10 patients, 80% hadfailed thrombolysis, p value< 0.001.Conclusion: Patients with No resolution of ST segment at 90min of thrombolysis had frequent adverse events and highermortality when compared to patients with partial and completeST segment resolution.en_US
dc.identifier.affiliationsSenior Resident, Department of General Medicine, Shyam Shah Medical College and Sanjay Gandhi Memorial Hospital, Rewaen_US
dc.identifier.affiliationsSenior Resident, Department of General Medicine, Shyam Shah Medical College and Sanjay Gandhi Memorial Hospital, Rewa, Indiaen_US
dc.identifier.citationMandal Ranjana, Yadav Kiran. Assessment of ST Segment Resolution as a Predictor of Outcome in Acute Myocardial Infarction after Thrombolysis. International Journal of Contemporary Medical Research . 2019 Aug; 6(8): h1-h5en_US
dc.identifier.issn2393-915X
dc.identifier.issn2454-7379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/202494
dc.languageenen_US
dc.publisherInternational Society for Contemporary Medical Researchen_US
dc.relation.issuenumber8en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.21276/ijcmr.2019.6.8.10en_US
dc.subjectAcute Coronary Syndrome (CAD)en_US
dc.subjectECGen_US
dc.subjectST Segment Elevation MI,ST Segment Resolutionen_US
dc.subjectThrombolysis.en_US
dc.titleAssessment of ST Segment Resolution as a Predictor of Outcome in Acute Myocardial Infarction after Thrombolysisen_US
dc.typeJournal Articleen_US
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