Acute Myocardial Infarction (AMI) Diagnosis; Impact of Technology in Developing Highly Sensitive Biomarkers and Assays

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dc.contributor.authorOsafo, Ren_US
dc.contributor.authorOlatunji, S. Hen_US
dc.contributor.authorNduka, C. L.en_US
dc.date.accessioned2023-07-21T11:29:26Z
dc.date.available2023-07-21T11:29:26Z
dc.date.issued2022-06
dc.description.abstractAcute myocardial infarction (AMI), a cardiovascular disease have been known to cause high morbidity and mortality rate in several countries. Hence, several serum biomarkers have evolved as a standard and bedrock for its diagnosis one of which is, cardiac troponin. This cardiac biomarker's accurate and rapid detection is critical in reducing the risk of heart attack-related complications. However, the delay experienced in the determination of a patient’s clinical state, coupled with the time of admitting them to the hospital depicts the need for improving diagnosing AMI by developing a highly sensitive biomarker. In this review we discuss, biomarkers and immunoassays employed in diagnosing acute myocardial infarction. Specifically, we reviewed and discussed cardiac troponin, a widely used biomarker. Subsequently, we discuss various methods used in assessing its performance and how technology has helped in developing more sensitive cardiac troponin to fast track its rate of diagnosis. At the end, we propose the integration of several disciplines from nanotechnology to biotechnology to develop a robust medical diagnostic system to facilitate disease diagnosis and help save lives.en_US
dc.identifier.affiliationsSchool of Health and Life Science, University of the West of Scotland, Paisley Campus, Scotland, United Kingdom.en_US
dc.identifier.citationOsafo R, Olatunji S. H, Nduka C. L.. Acute Myocardial Infarction (AMI) Diagnosis; Impact of Technology in Developing Highly Sensitive Biomarkers and Assays. Cardiology and Angiology: An International Journal. 2022 Jun; 11(4): 124-134en_US
dc.identifier.issn2347-520X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220287
dc.languageenen_US
dc.publisherSciencedomain Internationalen_US
dc.relation.issuenumber4en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.9734/ca/2022/v11i430215en_US
dc.subjectAcute myocardial infarctionen_US
dc.subjecttroponinen_US
dc.subjectassaysen_US
dc.subjectdiagnosisen_US
dc.subjectsensitivityen_US
dc.titleAcute Myocardial Infarction (AMI) Diagnosis; Impact of Technology in Developing Highly Sensitive Biomarkers and Assaysen_US
dc.typeJournal Articleen_US
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