Sirolimus: a new immunosuppressant.

No Thumbnail Available
Date
2005-10-08
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Though organ transplantation has evolved in many a ways over the years, it is not without the disadvantage of causing rejections. Cyclosporin, azathioprine and corticosteroids are time tested and efficacious; however each is accompanied with its own array of disadvantages. Sirolimus is a relatively new immunosuppressant isolated from a macrolide antibiotic. It may have a beneficial role in prophylaxis of rejection as well as treatment of refractory rejection. It also has antifungal, antitumor and anti-smooth muscle proliferative roles.
Description
29 references.
Keywords
Citation
Mukherjee T, Shah BV. Sirolimus: a new immunosuppressant. Journal of the Association of Physicians of India. 2005 Oct; 53(): 885-90