Topical lincomycin gel in acne vulgaris: a multicentric placebo controlled study.
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Date
2003-07-24
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Abstract
INTRODUCTION: Acne vulgaris is commonly treated with topical antibacterials. We evaluated lincomycin gel, a new topical formulation for mild to moderate acne.
MATERIAL AND METHODS: A multicentric, randomized, double blind, placebo controlled, clinical trial was conducted with lincomycin hydrochloride in 2% gel form in 200 patients with grade II and grade III acne. The severity of acne lesions was noted at baseline and after 4 weeks.
RESULTS: About 70% cases in the study group showed a good to excellent response, which was significantly more as compared to 23% in the placebo group. The frequency and severity of adverse reactions in the two groups were similar.
CONCLUSION: Lincomycin hydrochloride gel is an effective and safe treatment option for mild to moderate acne vulgaris.
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Sharma AD, Gupte PD, Sundaram M, Janaki VR, Rege VL, Bilimoria FE, Arora J. Topical lincomycin gel in acne vulgaris: a multicentric placebo controlled study. Indian Journal of Dermatology, Venereology and Leprology. 2003 Jul-Aug; 69(4): 271-3