Strain improvement studies on production of cephalosporin C from Acremonium chrysogenum ATCC 48272.

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Date
2003-02-12
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Abstract
Strain development for antibiotic production has been an essential prerequistie for efficient production process. Studies were carried out to produce high antibiotic yield strain by using UV and N-methyl-N1-nitro-nitrosoguanidine (NTG) as mutagens. A superior mutant (PNTG-22) with a productivity of 2.4 time (810-1995 microg/ml higher than, the parent strain was produced.
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Ellaiah P, Kumar JP, Saisha V, Sumitra JJ, Vaishali P. Strain improvement studies on production of cephalosporin C from Acremonium chrysogenum ATCC 48272. Hindustan Antibiotics Bulletin. 2003 Feb-2004 Nov; 45-46(1-4): 11-5
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https://imsear.searo.who.int/handle/123456789/2238
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Hindustan Antibiotics Bulletin