Cinnamomum zeylanicum (Cinnamon) Derived Phytochemicals against Aspartate Semialdehyde Dehydrogenase of Aspergillus fumigatus Causing Aspergillosis
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Date
2020-05
Journal Title
Journal ISSN
Volume Title
Publisher
SCIENCEDOMAIN international
Abstract
Aspergillosis is an infection caused by a type of fungus. The illnesses is caused by aspergillosis infection and usually attack the respiratory system, but their signs and severity vary greatly. It has already been established that plant Cinnamomum zeylanicum belonging to the Lauraceae family has the potential to help controlling aspergillosis. This work is focused on the identification of the particular phytochemical responsible for inhibiting and decreasing the effect of aspergillosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that cinnamic acid can effectively deactivate aspergillosis.
Description
Keywords
Phytochemical, Cinnamomum zeylanicum, Aspergillus fumigates
Citation
Jena Biswajit, Muni Minati Rani, Prusty P. K., Jha Sunil, Bhatttacharyay Deepankar. Cinnamomum zeylanicum (Cinnamon) Derived Phytochemicals against Aspartate Semialdehyde Dehydrogenase of Aspergillus fumigatus Causing Aspergillosis. Journal of Pharmaceutical Research International. 2020 May; 32(7): 84-87