Please use this identifier to cite or link to this item: https://imsear.searo.who.int/handle/123456789/215476
Title: Lateral transfer of organophosphate degradation (opdopd) genes among soil bacteria: mode of transfer and contributions to organismal fitness
Authors: Siddavattam, Dayananda
Yakkala, Harshita
Samantarrai, Devyani
Keywords: phosphotriesterases
opd gene
mpd gene
lateral gene transfer
molecular evolution.
Issue Date: Feb-2019
Publisher: Indian Academy of Sciences
Citation: Siddavattam Dayananda, Yakkala Harshita, Samantarrai Devyani. Lateral transfer of organophosphate degradation (opdopd) genes among soil bacteria: mode of transfer and contributions to organismal fitness. Journal of Genetics. 2019 Feb; 98: 1-10
Abstract: Genes encoding structurally independent phosphotriesterases (PTEs) are identified in soil bacteria. These pte genes, often identified on mobilizable and self-transmissible plasmids are organized as mobile genetic elements. Their dissemination through lateral gene transfer is evident due to the detection of identical organophosphate degradation genes among soil bacteria with little orno taxonomic relationship. Convergent evolution of PTEs provided selective advantages to the bacterial strain as they convert toxic phosphotriesters (PTs) into a source of phosphate. The residues of organophosphate (OP) compounds that accumulate in a soil are proposed to contribute to the evolution of PTEs through substrate-assisted gain-of-function. This review provides comprehensiveinformation on lateral transfer of pte genes and critically examines proposed hypotheses on their evolution in the light of the short half-life of OPs in the environment. The review also proposes alternate factors that have possibly contributed to the evolution and lateral mobility of PTEs by taking into account their biology and analyses of pte genes in genomic and metagenomic databases.
URI: http://imsear.searo.who.int/handle/123456789/215476
ISSN: 0022-1333
0973-7731
Appears in Collections:Journal of Genetics

Files in This Item:
File Description SizeFormat 
jmsh2019v98poooo1.pdf2.07 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.