Dexamethasone As Adjuvant To Intratheacal Bupivacaine

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Date
2019-01
Authors
Kishnani, Kanhaiya Lal
Dubey, Anuj
Jain, Priya
Journal Title
Journal ISSN
Volume Title
Publisher
World Wide Journals
Abstract
Spinal Analgesia is most preferred technique of regional analgesia for surgeries below umbilical region. The most commonly used drug is Bupivacaine heavy for the procedures lasting for 90 to 120 minutes. Sometimes procedures last longer requiring supplementation of anaesthesia or sedation. Various additives have been tried for prolongation of analgesia duration like Epinepherine, clonidine and opiods. Opiods can prove risky in elderly patients. Corticosteroids have shown positive effect on quality of sensory blocks and post operative analgesia on peripheral nerves. The purpose of this study was to evaluate the effect of Dexamethasone as adjuvant to intrathecal Bupivacaine, on onset time and duration of spinal analgesia. Material and Method: Sixty patients between 18 to 65 years of age belonging to ASA group I and II were studied. Patients were divided into two groups of 30 patients each. Study group received intrathecal 15 mg (3 ml) of 0.5% hyperbaric Bupivacaine heavy and 8 mg (2.0ml) of preservative free Dexamethasone(Total 5.0 ml solution) and control group received intrathecal 15 mg (3 ml) of 0.5% hyperbaric Bupivacaine heavy with 2.0 ml normal saline (Total 5.0 ml solution). Highest level of sensory block was noted and marked. It was evaluated every 5 minutes till 4 sensory segment level regression from highest level. Onset time and duration of sensory block were noted. Patients were monitored in post operative period for any symptoms. Conclusion: Addition of Dexamethasone with Bupivacaine has shown prolongation of duration of sensory block and decreased the requirement of analgesics in postoperative management
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Keywords
Spinal Analgesia, Bupivacaine, Dexamethasone
Citation
Kishnani Kanhaiya Lal, Dubey Anuj, Jain Priya. Dexamethasone As Adjuvant To Intratheacal Bupivacaine. Global Journal For Research Analysis. 2019 Jan; 8(1): 11-13