Comparative Study of Efficacy of Misoprostol Vs Dinoprostone Gel For Induction of Labour.
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Date
2015-07
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Abstract
Abstract
This study has been undertaken to compare the safety and efficacy of intra-vaginal misoprostol (PGE1
analogue) with intra-cervical dinoprostone (PGE2) in progress and induction of labour, the maternal side
effects and the foetal outcome. Group I comprised of 50 patients who underwent induction with misoprostol
vaginal tablets and Group II comprised of 50 patients who underwent induction with dinoprostone intra
cervical gel. Labour induction was considered successful if subjects delivered within 24 hours of initiation
of either of two methods. The maternal and foetal outcome were measured i.e., Bishop's score, time
intervals from induction to delivery, need for oxytocin, mode of delivery, maternal and foetal side effects.
The results of the present study show that the time intervals from induction-delivery intervals were
significantly shorter and the requirement of oxytocin was less for augmentation of the labour in the misoprostol
group than dinoprostone gel group. Intravaginal misoprostol is an effective agent for induction of labour
than intra cervical gel. The drug is easy to use, effective and safe to mother and the foetus. Misoprostol
can be routinely used for induction of labour than dinoprostone gel.
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Keywords
PGE1, PGE2, Induction of Labour
Citation
Swaran Gupta, Jyoti Hak, Dinesh Kumar. Comparative Study of Efficacy of Misoprostol Vs Dinoprostone Gel For Induction of Labour. JK Science Journal of Medical Education and Research. 2015 Jul-Sept. 17(3): 118-122.