Buprenorphine Significantly Prolongs Postoperative Analgesia in Intravenous Regional Anesthesia.
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Date
2015-07
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Abstract
Abstract
The current study was conducted to assess the efficacy of buprenorphine as an adjuvant in IVRA with 0.5
% lidocaine on 50 patients aged between 18-65 years, of either sex, scheduled for hand or forearm
surgery, who were divided randomly into two groups of 25 each. Group BL- Patients in the group received
10 ml of the preservative free lidocaine 2% diluted with saline, to a total volume of 40ml. Group BBPatients
in the group received 10 ml of the preservative free lidocaine 2% mixed with 1ml of buprenorphine
0.3mg diluted with saline to a total volume of 40ml. Various parameters like onset and duration of sensory
and motor blockade, degree of intra and postoperative analgesia, and requirement of the postoperative
analgesia and occurrence of any complications was noted. The time of onset for sensory block was
shorter in group BB (4.0 + 0.35min) as compared to group BL (6.0 + 0.6 min) (p=0.001). The onset of
motor block did not differ between the groups (p=0.05). In all patients in group BL analgesic duration did
not last for more than 2/3 hours (0.33 + 0.2 hours). In group BB, mean analgesic duration was 6.7 + 1.2
hours. Consumption of Diclofenac was also markedly lower in group BB (80.0 + 9.0mg vs. 214 + 33mg).
Addition of buprenorphine as an adjuvant in 0.5% preservative free lidocaine(40 ml volume) significantly
improves the postoperative analgesia and it also improved the onset of sensory block. Consumption of
Diclofenac was also markedly lower in group BB (80.0 + 9.0 mg vs. 214 + 33 mg).
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Keywords
Intravenous Regional Anesthesia, Buprenorphine, Lidocaine, Limb Surgery
Citation
Mukta Jitendra, Ashwani, Kumar, Anju Jamwal, Heena Gupta. Buprenorphine Significantly Prolongs Postoperative Analgesia in Intravenous Regional Anesthesia. JK Science Journal of Medical Education and Research. 2015 Jul-Sept. 17(3): 114-117.