Study of Forced Expiratory Volume in First Second (FEV1) and Ratio of Forced Expiratory Volume in First Second and Forced Vital Capacity in Percentage (FEV1/FVC%) in Pregnant Women.
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Date
2012-01
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Abstract
Background: A few data are available on the effects of pregnancy on pulmonary function in
different countries. But no such established data are available in our country. So we designed
this study in our population. Objectives: To observe the forced expiratory volume in first
second (FEV1) and ratio of forced expiratory volume in first second and forced vital capacity
(FEV1/FVC%) in different trimesters of normal pregnant women and to compare them with
those of healthy non-pregnant women. Materials and Methods: This observational and
analytical study was carried out in the department of Physiology, Dhaka Medical College
during July 2004 to June 2005. Total 100 women aged from 25 to 35 years without any recent
history of respiratory tract diseases were selected as study population. Among them, 75 normal
pregnant women were taken as experimental and 25 healthy non-pregnant women were taken
as control groups. The experimental group included 25 pregnant women in first trimester, 25 in
second trimester and 25 in third trimester. Forced expiratory volume in first second (FEV1),
ratio of percentage of forced expiratory volume in first second and forced vital capacity
(FEV1/FVC%) were measured in pregnant and non-pregnant control women. The FEV1 and
FEV1/FVC% were measured by using an ‘automatic spirometer’. Statistical analyses were
done by unpaired Student’s ‘t’ test between the study groups and p value <0.05 was taken as
significant. Results: The mean ± SD of measured values of FEV1 were 2.41 ± 0.87, 2.28 ±
0.59, 2.15 ± 0.74 and 1.89 ± 0.76 liters in non-pregnant women and in pregnant women during
first trimester, second trimester and third trimester. The mean ± SD of measured values of
FEV1/FVC% were 75.22 ± 16.77, 74.86 ± 11.06, 74.42 ± 17.43 and 71.81 ± 15.87% in nonpregnant
women and in pregnant women during first trimester, second trimester and third
trimester. Conclusion: The FEV1 and FEV1/FVC% were significantly lower in third trimester
pregnant women than that of non-pregnant and first trimester of pregnant women and
FEV1/FVC% gradually decreased from first to third trimester of pregnant women.
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Keywords
Forced expiratory volume in first second, Forced vital capacity, Pregnant women
Citation
Sunyal Dipok Kumar, Amin Md Ruhul, Yasmin Ayesha, Molla Golam Morshed, Ali Md Liakat, Sultana Masuda. Study of Forced Expiratory Volume in First Second (FEV1) and Ratio of Forced Expiratory Volume in First Second and Forced Vital Capacity in Percentage (FEV1/FVC%) in Pregnant Women. Journal of Enam Medical College. 2012 Jan; 2(1): 29-28.