Adverse Drug Reaction Monitoring in Psychiatry Outpatient Department of a Tertiary Care Teaching Hospital.
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Date
2014-10
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Abstract
To study the pattern of adverse drug reactions (ADR) in patients attending psychiatry OPD of a tertiary
care teaching hospital. Patients attending psychiatry OPD with ADRs due to drugs prescribed for various
psychiatric illnesses over a period of 1year were included in the study. Adverse event history, medication
history and other relevant details were entered in the PvPI format. Causality was assessed by WHOUMC
criteria. A total of 103 ADRs were reported from 85 prescriptions with a female preponderance.
Majority of ADRs (45.7%) were seen with antidepressants as they were the commonly prescribed drugs
followed by antipsychotics (33.3%) and others by sedative hypnotics and anticonvulsants. ADRs like
somnolence topped the list (21.9%) followed by weight gain (18.4%), akathesia (6.8%) and drug induced
restless legs syndrome (RLS) (5.8%). The reported ADRs were assessed for causality and maximum
(80.6%) belong to the "possible" category. Maximum ADRs were seen with antidepressants followed by
antipsychotics. Sedation and weight gain were the most commonly occurring ADRs.
Description
Keywords
Adverse Drug Reactions, Pharmacovigilance, Psychotropic Drugs, Psychiatric Illness
Citation
Sharma Taruna, Vishwakarma Kirti, Dhasmana D C, Gupta Ravi, Kalra Juhi, Sharma Upasana. Adverse Drug Reaction Monitoring in Psychiatry Outpatient Department of a Tertiary Care Teaching Hospital.JK Science Journal of Medical Education and Research. 2014 Oct-Dec; 16(4): 156-160.