Correlation between Acetaminophen Consumption and CSF Glucose Level in Febrile Convulsion.
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Date
2011-10
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Abstract
Hyperglycemia and hyperglycorrhagia common occur in children with febrile seizures. Rapid release of
cortisol and adrenaline after seizures as a stress reaction induce elevated glucose concentration in Cerebral
Spinal Fluid (CSF). The purpose of this study was to assess the correlation between acetaminophen
consumption and CSF glucose level in children with febrile convulsion.This cross- sectional study was
performed over 3-18 months old children who were admitted at pediatric section of teaching hospital
during 7 years. Comparisons between the mean CSF glucose concentrations in the children who taken and
no taken acetaminophen during 6 hours before convulsion was performed using Student's t-test and Mann-
Whitney test.The glucose level in the CSF of children who no taken acetaminophen (82±8 mg/dl) was
significantly higher than children taken acetaminophen (53±4 mg/dl). (P=0.0001).The use of acetaminophen
before convulsion decrease CSF glucose concentration in febrile convulsive children
Description
Keywords
Acetaminophen, CSF Glucose, Febrile Convulsion
Citation
Fahimesh Ehsanipour, Minoo Gharouni, Maryam Ardalam, Ali Hoseinpoor Rafati, Rojin Amin.Correlation between Acetaminophen Consumption and CSF Glucose Level in Febrile Convulsion. JK Science Journal of Medical Education and Research. 2011 Oct-Dec;13(4): 176-178