Rosai-Dorfman Disease.
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Date
2010-10
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Abstract
Rosai-Dorfman Disease (RDD) or Sinus Histiocytosis with massive lymhadenopathy (SHML) is a rare,
benign proliferative disorder of histiocytes, sometimes showing familial incidence. It is mainly characterized
by painless bilateral cervical lymph node enlargement and is often associated with fever and leucocytosis.
It presents in the first or second decades of life, though any age group can be affected. Without the
awareness about RDD, the diagnosis of RDD is unexpected especially in South East Asian Countries
where certain lymphadenopathies such as tuberculosis, metastatic nasopharayngeal carcinoma and
lymphomas are common. RDD is commonly missed and so its revision would seem worthwhile, this case
illustrating the disappearance of the lymphadenopathy without treatment.
Description
Keywords
Sinus histiocytosis with massive lymphadenopathy (SHML), Lymphophagocytosis. Emperipolesis, Rosai- Dorfman disease (RDD)
Citation
Sharma Sindhu, Bhardwaj Subhash, Hans Deepa. Rosai-Dorfman Disease. JK Science Journal of Medical Education and Research. 2010 Oct-Dec; 12(4): 194-196