Sympathetic Nerve Function Status in Follicular and Late Luteal Phases of Menstrual Cycle in Healthy Young Women.
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Date
2010-12
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Abstract
Background: Autonomic nerve function status may be changed during follicular and late luteal
phases of menstrual cycle due to fluctuations of serum estrogen and progesterone level.
Objective: To observe the sympathetic nerve function status during follicular and late luteal phases of
menstrual cycle and their relationships with serum estrogen and progesterone in healthy young
womens. Methods: This cross-sectional study was carried out in the Department of Physiology, Sir
Salimullah Medical College, Dhaka from 1st January 2009 to 31st December 2009.A total number of
thirty (30) apparently healthy unmarried women with age ranged from 20-25 years were investigated.
Two simple autonomic nerve function tests, like fall of systolic blood pressure (SBP) on standing and
rise of diastolic blood pressure (DBP) during handgrip were done to assess sympathetic activity.
Serum estrogen and progesterone levels were also measured by AxSYM method. All these tests were
performed in both follicular and late luteal phases of menstrual cycle. Data were analysed by paired
student’s ‘t’ test and Pearson’s correlation coefficient test as applicable. Results: Mean resting heart
rate was significantly (p<0.01) increased in late luteal phase than that of follicular phase. Mean resting
systolic blood pressure was significantly (p<0.01) increased and resting diastolic blood pressure was
non-significantly increased in late luteal phase than those of follicular phase. Again, significantly
(p<0.05) increased value of fall of systolic blood pressure after standing from lying and non-significant
increased value of rise in diastolic blood pressure after sustained handgrip were observed in late
luteal phase. The mean value of serum estrogen was non-significantly and serum progesterone was
significantly (p<0.001) increased in late luteal phase than those of follicular phase. Conclusion: From
this study it can be concluded that sympathetic activity is increased in late luteal phase of menstrual
cycle. In addition, increased sympathetic activity during late luteal phase might be the cause of
premenstrual syndrome (PMS) in some women.
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Keywords
Sympathetic nerve functions, progesterone
Citation
Choudhury Rama, Jahan Nasim, Sultana Nayma, Akter Rezina, Khanum Ayesha Akhter. Sympathetic Nerve Function Status in Follicular and Late Luteal Phases of Menstrual Cycle in Healthy Young Women. Journal of Bangladesh Society of Physiologists. 2010 Dec; 5(2): 80-88.