Pharmacognostical Standardization and HPTLC Fingerprint of Alstonia Scholaris Linn. Bark.
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Date
2014-01
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Abstract
There is increasing global interest in herbal and other forms of traditional medicines. Herbs have long
been an important source of numerous effective drugs. As per World Health Organization recommendations, there is
a need for investigation of traditional medicinal plants for their potential therapeutic efficacy. The bark of Alstonia
scholaris (L.) R. Br. (Family: Apocynaceae) locally known as ‘Sapthaparni’ or ‘Satwid’, is reported to have
anticancer, antihelminthic, antidiarrhoeal, antiasthamatic, antimalarial etc. The present work embodies the study
carried out for quality control of herbal drugs which comprises of macroscopy, microscopy, physicochemical
properties, phytochemical analysis, fluorescence analysis and HPTLC fingerprint. The anatomical markers present
were found to be stone cells, sclereids, cork cells, fibers and prismatic crystals of calcium oxalate. Methanol soluble
extractive value was found to be higher than Water, Ethanol and Petroleum ether soluble extractive values.
Preliminary phytochemical analysis revealed the presence of tannins, alkaloids, steroids, amino acids, fats, fixed oil,
glycosides, proteins, starch and flavonoids. A unique HPTLC fingerprint for A. scholaris (L.) R. Br. bark was
developed. Results of the present study on pharmacognostical and phytochemical investigation of A. scholaris (L.) R.
Br. bark will be helpful in developing standards for quality, purity and sample identification of this plant.
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Keywords
Alstonia scholaris L.,, pharmacognosy, phytochemical analysis, HPTLC fingerprint
Citation
Patil Avinash, Vadera Khyati, Patil Darshana, Phatak Anita, Chandra Naresh. Pharmacognostical Standardization and HPTLC Fingerprint of Alstonia Scholaris Linn. Bark. International Journal of Applied Biology and Pharmaceutical Technology. 2014 Jan-Mar; 5(1): 41-49.