Induced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome.

Tripathi, Mukesh; Singh, Prabhat Kumar; Kumar, Naresh; Pant, Kailash Chandra

Induced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome.

Date

2009-01-13

Authors

Tripathi, Mukesh

Singh, Prabhat Kumar

Kumar, Naresh

Pant, Kailash Chandra

Abstract

The state of vasoplegia in immediate post-cardiopulmonary bypass period is characterized by severe hypotension, supranormal cardiac output, low systemic vascular resistance (SVR), and resistance to vasoconstrictors. We could successfully use induced mild hypothermia to increase SVR, and could avoid very high doses of nor-epinephrine (>0.3 mcg/kg/min) in the background of severe pulmonary hypertension (systolic pulmonary pressure> 90 mmHg). Its effects such as decreased oxygen demand, positive inotropy and better right ventricle performance probably helped to improve oxygenation in presence of pulmonary oedema.

Citation

Tripathi M, Singh PK, Kumar N, Pant KC. Induced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome. Annals of Cardiac Anaesthesia. 2009 Jan-Jun; 12(1): 49-52