Are Biodegradable Third Generation Drug Eluting Stents the Answer to Instent Restenosis.
Loading...
Date
2014-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The third generation biodegradable Drug Eluting Stent (DES) are being evaluated and
being introduced in clinical practice. They have been DESigned to overcome limitations
associated with durable polymer and a persistent metallic stent scaffold which could be
related to late target lesion revascularization (TLR) and very late stent thrombosis (VLST).
Although a recent pooled data analysis found that biodegradable polymer stents were
superior for TLR and VLST compared with first generation Sirolimus Eluting Stent (SES),
superiority has not been demonstrated against second generation Everolimus eluting
stents (EES) and is yet to be conclusively proven in randomized trials. This paper reviews
the key features, recent trial data, and future directions of the third generation of DES
technology including stents with fully biodegradable scaffolds, stents with biodegradable
polymer, and polymer free stents.
Description
Keywords
Biodegradable, coronary, stents
Citation
Amritphale Amod, Amritphale Nupur, Ahsan Chowdhury H. Are Biodegradable Third Generation Drug Eluting Stents the Answer to Instent Restenosis. Cardiology and Angiology An International Journal. 2014 Jan-Mar; 2(1): 15-40.