Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms.
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Date
2013-04
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Abstract
A rapid and simple method for simultaneous determination of Chlorpheniramine Maleate (CPM) and Phenylpropa-nolamine Hydrochloride (PPM) by first derivative UV spectrophotometry has been developed in combined pharmaceutical dosage forms. The proposed method was successfully applied for the determination of drugs in physical mixture and commercial formulations and results showed good linearity, precision and reproducibility.
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Keywords
Derivative, UV absorption, spectral overlap, principle maxima, wavelength range, analytical signal
Citation
Kaura Arun, Gupta Vikas, Roy G S, Kaura Monika. Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms. International Current Pharmaceutical Journal. 2013 Apr 2(5): 97-100.