Browsing by Author "Singh, R B"

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    The Adverse Effects of Wealth on Cardiovascular Health: A Scientific Statement of the International College of Cardiology.
    (2013-01) Singh, R B; Hristova, K; Muthusamy, V V; Rastogi, S S; Basu, T K; Toda, E; Takahashi, T; Fedacko, J; Pella, D; Meester, F De; Wilson, D W; Mondal, R N; Ishaq, M; Mohideen, M R
    Background and Aims: Increase in economic status may be associated with increased consumption of Western type of foods and sedentary behaviour. In the present review, we discuss that increase in wealth may be associated with adverse effects on health behaviour Study Design and Methods: Internet search and discussion with colleagues. Results: Review of studies indicate that with increase in wealth, there is increased consumption of high fat, ready prepared foods and decrease in physical activity in most of the countries resulting in obesity and metabolic syndrome, leading to cardiovascular diseases (CVDs) and other chronic conditions. Many experts during the United Nations High Level Meeting in Sept 2011, misinterpreted the WHO estimates and proposed that, of total deaths, 22·4 million arise in the poorest countries, and 13.7 million in high-income and upper-middle-income countries and therefore poverty may be the major cause of deaths due to non-communicable diseases (NCDs). A recent study shows that 57.0 % of deaths in adults (aged 25-64 years) were due to CVDs and other chronic diseases, 25.5% due to communicable diseases and 15.9% due to injury and accidents. The deaths due to NCDs were highly prevalent among higher social classes compared to lower social classes who had greater deaths due to communicable diseases. It is interesting to know from new data from United States, that there is ‘Wealth’ without cardiovascular health in America. The whole world is likely to have the same scenario in the near future. Conclusions: Increase in wealth may be associated with altered health behaviour; greater consumption of unhealthy foods, tobacco consumption, mental load and sedentary behaviour resulting in increased risk of deaths due to CVDs and other chronic diseases which may change with knowledge about health education. Wealth may cause extension in life by buying of expensive drug therapy, intervention and surgery which are known to add income and employment in the west.
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    Aluminium phosphide poisoning.
    (1994-10-01) Singh, R B
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    Auto-amputation of vermiform appendix.
    (1995-04-01) Singh, R B; Gopal, M; Dahiya, R S; Bhargava, J S
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    The calcium paradox and the blood pressure.
    (1986-05-01) Singh, R B
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    Cardiovascular manifestations of aluminium phosphide intoxication.
    (1989-09-01) Singh, R B; Rastogi, S S; Singh, D S
    Aluminium phosphide (ALP) a major suicidal agent in the developing countries is freely available as grain fumigant. It is highly toxic to lungs, heart and blood vessels causing pulmonary oedema, shock and arrhythmias. There is massive focal myocardial damage resulting in raised cardiac enzymes. Clinical manifestations were nausea and vomiting (32), dyspnoea and palpitations (25 each), cyanosis (12), hypotension (12) and shock (15). Cardiac arrhythmias were present in 28 cases and hypermagnesaemia in 13 patients. Mean serum magnesium level (1.95 +/- 0.2O, mEq/L) was significantly raised compared to mean magnesium level in control subjects (1.62 +/- 0.23 mEq/L). Hypermagnesaemia occurs due to myocardial and liver damage. Out of 32 cases studied, 22 died 18 within 24 hours of ALP ingestion. Thirty two cases of ALP were studied.
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    Chronic active hepatitis and cardiomyopathy.
    (1974-07-01) Singh, R B; Singh, V P; Katiyar, B C
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    Chronic illness among rural population.
    (1988-03-01) Garg, S K; Mishra, V N; Bhatnagar, M; Singh, R B; Srivastava, R B; Garg, A
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    Civilian vascular trauma: an experience of 54 cases.
    (1996-02-01) Bhargava, J S; Kumar, R; Singh, R B; Makkar, A
    Fifty-four patients with civilian vascular injuries of the extremities caused by blunt trauma in 41 patients and by penetrating trauma in 13 patients were evaluated. Twenty-nine patients (53.7%) had associated fractures/dislocations and 19 sustained concomitant venous injuries. Twenty-nine patients (53.7%) came with a lagging period of more than 12 hours. Vascular injuries were diagnosed both clinically and by Doppler examination. In patients with equivocal findings, arteriography was performed. Arterial repair was done in 19 patients and saphenous vein interposition grafting was done in 2 patients. Fifteen patients required fasciotomy. Amputation was done in 13 patients (24.07%). It is concluded that the time lag, incorrect and incomplete assessment, and the reluctance to perform fasciotomy early and completely are some of the factors responsible for poor results.
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    Coenzyme Q in cardiovascular disease.
    (1998-03-29) Singh, R B; Niaz, M A; Rastogi, V; Rastogi, S S
    Coenzyme Q10 or ubiquinone normally present in many plant and animal cells is an antioxidant. Coenzyme Q10 deficiency has been observed in patients with congestive heart failure, angina pectoris, coronary artery disease, cardiomyopathy, hypertension, mitral valve prolapse and after coronary revascularization. Coenzyme Q10 is involved in the synthesis of ATP and hence is useful in preventing cellular damage during ischaemia-reperfusion injury. The clinical benefits are mainly due to its ability to improve energy production, antioxidant activity, and membrane stabilizing properties. Several studies showed that coenzyme Q could be useful in patients with congestive heart failure, angina pectoris, cardiomyopathy, coronary artery disease and in the preservation of myocardium. Coenzyme Q10 is normally present in the low density lipoprotein cholesterol fraction and inhibits its oxidation. It can also regenerate vitamin E. Coenzyme Q10 is known for producing minor gastrointestinal discomfort and elevation in SGOT and LDH when used.
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    Congenital diaphragmatic hernia past infancy.
    (1988-09-01) Sharma, L; Singh, R B
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    Coronary artery disease in South Asians.
    (1997-03-01) Singh, R B
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    Diet, diabetes and atherosclerosis.
    (1990-08-01) Singh, R B
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    The diet-heart question in 1985?
    (1986-04-01) Singh, R B
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    Digoxin Q-T prolongation.
    (1989-02-01) Singh, R B
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    Effect of dietary phytoestrogens on human growth regulation: imprinting in health & disease.
    (2014-11) Griffiths, K; Wilson, D W; Singh, R B; De Meester, F
    This group has advocated a return to the notional Palæolithic diet with fruits, vegetables, roots, leaves, seeds, phytochemical antioxidants and proteins, etc. Phytoestrogens, viz. lignans, isoflavonoids and flavonoids are weak oestrogenic constituents of such a diet and may have a considerable impact on human health and disease. The aim of this paper was to conduct a preliminary overview of about 2000 research-led studies from the 1930s to the present time reported in the literature on flavonoids/isoflavonoids/lignans and to assemble evidence for a future strictly formal literature review on the health benefits and risks of flavonoids in a variety of diseases.
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    Effect of morphine on electroshock seizures in rat.
    (1978-09-01) Tripathi, K D; Singh, R B
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    Enteropathogenic Escherichia coli diarrhoea in Malaysian children.
    (1975-03-01) Jegathesan, M; Singh, R B; Kanaganayagy, M; Soon, L E
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    An epidemiological study of coronary heart disease (CHD).
    (1995-09-01) Singh, R B; Niaz, M A