Browsing by Author "Shivani, Randev"

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    Wheezing in Preschool Children and Total IgE Levels: A Birth Cohort Study
    (Indian Academy of Pediatrics, 2020-03) Jat, Kana Ram; Kumar, Prawin; Mukherjee, Aparna; Shivani, Randev; Bipin, Jose; M, Kalaivani; Lodha, Rakesh; Kabra, Sushil K
    Objectives: To evaluate association between total IgE levels and wheezing in preschoolchildren from India. Methods: Datawere collected in a prospective birth cohort study relatedto wheezing till three years of age. Total IgE was measured at enrolment, at one year and twoyears of age and correlated with wheezing episodes. Results: A total of310 (167 boys)children were enrolled. Total IgE levels increased with age (P<0.001). Overall, 101 (32.6%)children had 182 episodes of wheezing. The median (IQR) total IgE levels in children withwheezing and without wheezing were similar at one year [42.1 (12.7, 93.5) vs 41.9 (17.1,96.7) kU/L; P=0.39] and two years of age [62.8 (32.4, 212.0) vs 75 (25.8, 173.0) kU/L,P=0.92). Conclusion: Total IgE levels increased with age and were not different in preschoolchildren with and without wheezing.