Browsing by Author "Chakraborty, R"
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Item Angioplasty versus coronary artery by-pass surgery: a reappraisal.(1999-07-22) Chakraborty, RRevascularisation is the main principle of treatment of obstructive coronary artery disease. This technique is available either by catheter intervention like angioplasty or by-pass surgery. The superiority of one over the other is still undetermined. In symptomatic single vessel disease angioplasty may be a better option than by-pass surgery. In two-vessel coronary artery disease angioplasty may also be preferred especially with good left ventricular function. In patients with double-vessel disease particularly involving proximal left anterior descending artery in association with diabetes mellitus surgery has better long term results. In multivessel disease by-pass surgery is a preferred option although initial results of angioplasty in this group may be very satisfactory. The incidence of further intervention either by surgery or repeat angioplasty is high in patients undergoing angioplasty in multivessel disease. Left main stem disease should be dealt with by-pass surgery. With continued advancement in the revascularisation technology of coronary artery disease both in catheter intervention and surgical fronts there is no room for unequivocal or universal strategy plan in the management of coronary artery disease. Both the techniques are complimentary to each other. Cost consideration is a major consideration in India. Choice should be made after proper evaluation of coronary anatomy, underlying clinical condition, local experience, social and especially economic circumstances.Item Differential catalytic inhibition of lactoperoxidase and rat submaxillary peroxidase by antiserum raised against pure lactoperoxidase.(1986-08-01) Chakraborty, R; Hati, R NItem Distribution of HIV-1 resistance-conferring polymorphic alleles SDF-1-3'A, CCR2-64I and CCR5-Delta32 in diverse populations of Andhra Pradesh, South India.(2001-12-04) Ramana, G V; Vasanthi, A; Khaja, M; Su, B; Govindaiah, V; Jin, L; Singh, L; Chakraborty, RPolymorphic allelic variants of chemokine receptors CCR2 and CCR5, as well as of stromal-derived factor-1 SDF-1, the ligand for the chemokine receptor CXCR4, are known to have protective effects against HIV-1 infection and to be involved with delay in disease progression. We have studied the DNA polymorphisms at the loci that encode these proteins in 525 healthy individuals without any history of HIV-1 infection from 11 diverse populations of Andhra Pradesh, South India. The two protective alleles SDF-1-3'A and CCR2-64I at the SDF-1 and CCR2 loci, respectively, are present in all populations studied, although their frequencies differ considerably across populations (from 17% to 35% for the SDF-1-3'A allele, and from 3% to 17% for CCR2-64I). In contrast the CCR5-Delta32 allele is observed only in three populations (Yamani, Pathan and Kamma), all in low frequencies (i.e. 1% to 3%). The mean number of mutant alleles (for the three loci together) carried by each individual varies from 0.475 (in Vizag Brahmins) to 0.959 (in Bohra Muslims). The estimated relative hazard values for the populations, computed from the three-locus genotype data, are comparable to those from Africa and Southeast Asia, where AIDS is known to be widespread.Item DNA base sequence preference for adriamycin and nogalamycin binding.(1985-06-01) Choudhury, K; Chakraborty, R; Dhar, T C; Neogy, R KItem DNA polymorphism and clinical genetics.(1986-11-01) Chakraborty, RItem Effect of reserpine on peroxidase activity in submaxillary gland.(1987-04-01) Chakraborty, R; Hati, R N; Datta, A GItem Paternity exclusion by genetic markers in Indian populations.(1975-01-01) Chakraborty, R; Roychoudhury, A KItem A Study of Psychiatric Referrals in a Multidisciplinary Teaching Hospital.(2009-10) Kumar, P; Srivastava, S; Bhatia, M S; Rajinder, G; Raghav, S K; Chakraborty, R; RayaBetween April 2009 and June 2009, a three month period, a total of 130 inpatients from a tertiary care, multidisciplinary hospital were referred for psychiatric opinion. 35 cases were referred for attempted suicide and 95 cases for other reasons. An analysis of these two groups of referrals was done to study the referral trends. About 7% with organic disorders, 14.6% presented with drug dependence, 7.7% with schizophrenia and psychotic disorders, 22.3% presented with mood disorders. Our findings were like other Asian countries with a significant group comprising of dissociative disorder (hysteria) unlike west.