Browsing by Author "Begum, Z"

Now showing 1 - 8 of 8
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    Anti H.pylori IgM in Symptomatic and Asymptomatic Population.
    (2009-01-03) Sumona, A A; Hossain, M A; Musa, A K; Shamsuzzaman, A K; Mahmud, M C; Khan, M S; Ahmed, S; Begum, Z; Zahan, N A; Ahmed, M U; Debnath, C R; Anne, R A
    To evaluate the usefulness of specific IgM in the diagnosis of Helicobacter pylori infection, a cross sectional study was carried out in the Department of Microbiology, Mymensingh Medical College between July 2006 to June 2007. A total of 45 patients having upper gastrointestinal symptoms underwent endoscopy and were subsequently diagnosed as patients with gastritis, peptic ulcer (PU) and non-ulcer dyspepsia (NUD) and another 45 asymptomatic individuals aged 18-65 years, were included in the study. The serum samples of participants were tested for presence of anti-H pylori IgM by using ELISA method. The ELISA for anti H. pylori IgM provided sensitivity and specificity of 73.33%, 93.33% respectively.
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    Comparison between DOT EIA IgM and Widal Test as early Diagnosis of Typhoid Fever.
    (2009-01-03) Begum, Z; Hossain, M A; Musa, A K; Shamsuzzaman, A K; Mahmud, M C; Ahsan, M M; Sumona, A A; Ahmed, S; Jahan, N A; Alam, M; Begum, A
    A recently developed DOT enzyme immunoassay known as "Typhidot" for detecting IgM antibody against 50 KDa OMP antigen of Salmonella typhi, was evaluated on 100 clinically suspected typhoid fever cases and 40 age-sex matched controls, in the Department of Microbiology, Mymensingh Medical College during, the period from June 2006 to July 2007. Blood culture, Widal test, and DOT EIA for IgM test were performed in all patients. Among 100 clinically suspected typhoid fever cases, 35 were subsequently confirmed on the basis of positive blood culture for S. typhi and/or significant rising titre of Widal test. The DOT EIA IgM test could produce results within 1 hour. The result of the DOT EIA IgM test showed a good diagnostic value for typhoid fever. The sensitivity, specificity, positive and negative predictive value of the test was found as 91.42%, 90.00%, 88.88% and 92.30% respectively. On the other hand corresponding values for Widal test were of 42.85%, 85.00%, 71.42% and 62.96% respectively. Thus, The DOT EIA IgM seems to be a practical alternative to Widal test for early diagnosis of typhoid fever.
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    Doctors and the threat of nuclear war.
    (1998-07-11) George, T; Begum, Z; Amalorpavanathan, J
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    The Dunkel draft--a prescription for disaster.
    (1992-07-01) George, T; Amalorpavanathan, J; Begum, Z
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    Induction of apoptosis in AK-5 cells by rotenone involves participation of caspases.
    (1999-04-05) Khar, A; Ali, A M; Begum, Z; Pardhasaradhi, B V; Varalakshmi, C
    AK-5 tumour cells undergo apoptosis after treatment with rotenone an electron transport inhibitor and oligomycin which inhibits mitochondrial ATPases. Apoptotic process involves the induction of caspases 2 and 3, whereas caspase 1 does not seem to be participating in rotenone/oligomycin induced apoptosis. DEVD which is a specific inhibitor of caspase 3, inhibited apoptosis in AK-5 cells. We have also observed a significant lowering of intracellular pH in AK-5 cells which are induced into the apoptotic process by rotenone. These results suggest an important role for mitochondrial electron transport in the induction of apoptosis in AK-5 tumour cells.
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    PCR for mecA Gene of Methicillin Resistant Staphylococcus Aureus.
    (2009-01-03) Zahan, N A; Hossain, M A; Musa, A K; Shamsuzzaman, A K; Mahamud, M C; Mamun, A A; Paul, S K; Ahmed, S; Sumona, A A; Begum, Z; Alam, M; Yusuf, M A; Uddin, M S
    The study was under taken to detect mecA gene of methicillin resistant Staphylococcus aureus (MRSA) by PCR. It was carried out in the department of Microbiology, Mymensingh Medical College in collaboration with the Department of Medicine under the Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh between the periods from July 2006 to June 2007. A total of 40 S. aureus strains were used in this study. Isolates of S. aureus were identified by standard microbiology technique and their antimicrobial susceptibility test was done by disk diffusion method according to NCCLS. Minimum inhibitory concentration (MIC) of oxacillin was determined for all isolates by standard agar plate dilution method. All strains were tested for mecA gene by PCR. Out of 40 S. aureus strains 15(37.5%) were detected as MRSA by disk diffusion and agar dilution method but 10(25%) yielded mecA gene by PCR. Detection rate of MRSA by disk diffusion and agar dilution test showed significant difference to that by PCR (p<0.001).
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    Status of different immune cells during regression of a rat histiocytoma.
    (1993-09-01) Khar, A; Begum, Z; Manogaran, P S
    Status of CD4 and CD8 positive T-lymphocytes, natural killer cells and macrophages has been studied in animals which reject AK-5 histiocytoma. Analysis of immune cells which enter the tumour showed higher number of CD8 positive and NK cells around day 25 after tumour transplantation, suggesting their participation in tumour rejection.
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    The TRIPS agreement and pharmaceuticals.
    (1995-03-01) George, T; Begum, Z