Browsing by Author "Ahmad, S."
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Item GASTRO-INTESTINAL LYMPHOMA PRESENTING AS INTUSSUSCEPTION(Era's Lucknow Medical College & Hospital, Lucknow, 2021-06) Zaidi, N; Irfan, S; Tiwari, K; Lal, N; Ahmad, S.Extranodal Lymphomas are most commonly located in gastrointestinal tract. The most common cause of small intestinal obstruction in children is intussusception. However GI lymphomas are a rare cause of intussusception. So we are reporting a case of extranodal lymphoma in a female child presenting as intussusception of small intestine. a 9 years old female child presented with features of subacute intestinal obstruction. On examination a lump was felt in the abdomen. On further evaluation, a computed tomography (CT) revealed a possibility of lymphoma. The bowel segment was excised and sent for histopathological examination. On gross examination a growth was seen along with satellite lesion. 10 lymph nodes were also identified. Representative sections were taken. Microscopic examination showed the presence of medium size to large size lymphoid cells. After immunohistochemical staining a diagnosis of Non Hodgkins Lymphoma (Extranodal Marginal Zone) was made. 1 lymph node was positive for tumour invasion while other 9 were showing reactive hyperplasia. Since both lymphomas and intussesception are common in pediatric age group, lymphoma should always be kept as a differential diagnosis while dealing with a case of intussusception in pediatric age group.Item OMICRON-THE VARIANT OF CONCERN (VoC): A RAPID REVIEW(Era's Lucknow Medical College & Hospital, Lucknow, 2021-12) Shamsi, AS; Ghauri, MN; Ahmad, S.A new variant of coronavirus B.1.1.529. appeared on the scene, when discovered by the researchers in South Africa on Nov 24.2021. It is a heavily mutated variant of coronavirus discovered thus far with over 50+ mutations with 32 mutations over the spike protein itself. Spike proteins help the virus to bind to the bodily receptors of humans to gain entry inside. In comparison to the delta variant, which had nine mutations, it means that Omicron has better chances of evading the host immunity and is also more transmissible. And rightly so, it has been declared as a variant of concern(VoC) by the WHO. The presence of S- gene is of the determinants for the detection of the virus. But omicron seems to have missed this gene- being called as S-gene dropout or S-gene target failure (S- spike glycoprotein)