Browsing by Author "Agarwal, Anju"
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Item Clinical correlation of vitamin D in depression(Medip Academy, 2019-07) Sharma, Nitin; Bharti, Shantanu; Jilani, Abdul Qadir; Agarwal, Anju; Singh, Saloni; Sharma, RuchitaBackground: Literature has substantially advanced our understanding of the action of vitamin D in depression, much is still unknown concerning how vitamin D relates to dimensions of depression. Hence, authors aimed to examine the relationship of vitamin D in patients of depression, its correlation with the severity of depression and different symptom domains of depression.Methods: This Hospital based case control study included 75 patients with depression and 50 controls who were age and gender matched. Beck’s Depression Inventory II was used to assess the severity and symptom domains of depression. Vitamin D levels was assessed using Enhanced Chemiluminescence Technique.Results: Vitamin D deficiency was found significantly (<0.001*) among cases than controls. Significant (0.003*) inverse correlation was observed between severity of depression and vitamin D level.In cognitive symptoms, pessimism, punishment feeling, self-criticism, suicidal thoughts and worthlessness were found significantly higher among vitamin D deficient patients. However, in somatic-affective symptoms, crying, indecisiveness, loss of energy, irritability, concentration difficulty and being tired were the significant by prominent symptoms in vitamin D deficient patients.Conclusions: Vitamin D (<50 nmol/L) was found to be significantly associated with depressive symptoms with cognitive and somatic-affective symptoms being affected by vitamin D deficiency.Item Depression and anxiety in patients with epilepsy(Medip Academy, 2018-09) Gupta, Sanyam; Sharma, Nitin; Bharti, Shantanu; Sharma, Ruchita; Kohli, Ajay; Agarwal, Anju; Jilani, Abdul Qadir; Shukla, RituBackground: Anxiety and depression are commonly found in epileptic patients. However, the etiology behind the mechanism remains multifactorial, mostly because of variability in study settings. In order to fill the knowledge gap, we investigated the prevalence of anxiety and depression among epileptic patients and their correlation with certain demographic variables.Methods: In a Cross Sectional Out Patient Based Study, a total of 147 patients with epilepsy were recruited and evaluated for inclusion and exclusion criterion. Participants who met the inclusion criterion were assessed using standardized scales HARS and HADS rating scale for anxiety and depressive symptoms respectively.Results: 100 participants were included with mean age of 33.63 years for men and 30.16 years for females. 27% showed mild to severe anxiety and 21% had mild to moderate depression. Prevalence of both anxiety and depression was found more among females, singles, participants from urban background and having partial epilepsy. Significantly (p-0.020*) higher anxiety was seen in patients with partial epilepsy than those with generalized epilepsy.Conclusions: Individuals with partial epilepsy are more prone to get affected from comorbid disorder like anxiety and depression, especially females, singles and those from urban domicile.Item Kleine-Levin syndrome: a case report.(2015-02) Tiwari, Anshuman; Agarwal, Anju; Bharti, Shantanu; Kohli, AjayKleine-Levin syndrome is characterized as a periodic hypersomnia crisis as well as dietary and variable significant psychiatric symptoms. This case report is of 15 year boy who presented with characterstic features of hypersomnia, hyperphagia, affective features like irritability and cognitive disturbances in an episodic manner with spontaneous remission. Due to the above clinical presentation we made the diagnosis of Kleine-Levin syndrome in this patient who was started on psychostimulant and responded well on these medications.Item Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome With Behavioural Disturbance And Mental Retardation - A Case Report(Era's Lucknow Medical College and Hospital, 2017-01) Agarwal, Deeptanshu; Jilani, A.Q.; Srivastava, Priyadarshi; Gupta, S. B.; Agarwal, Anju; Kohli, AjayThe Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome affects 1 out of 4500 female in which there is underdeveloped or absence of female genitourinary system, vagina or uterus. It is transmitted as an autosomal dominant trait with an incomplete degree of penetrance and variable expressivity. The phenotypic expression of this syndrome involve anomaly of the reproductive system. The case “ MIss X” presented with episodes of disorganised behaviour (self injurious). Miss X was provisionally diagnosed as seizure disorder with mental retardation. Detailed evaluation marked the abesnce of reproductive system. This possiblility of dual association of a major physical/anatomical abnormality and psychological disorder in young adolescent girl, is being presented here after taking valid consent.Item Recommendations of National Consultative Meeting on Polio Eradication, 2010; Polio Eradication Committee, Indian Academy of Pediatrics (IAP).(2010-09) Vashishtha, Vipin M; Kalra, Ajay; John, T Jacob; Thacker, Naveen; Agarwal, Anju; Ugra, Deepak