Browsing by Author "Agarwal, A K"
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Item Abnormal haemoglobins in Nepali Gorkhas.(1977-11-01) Gupta, S C; Mehrotra, T N; Sharma, N P; Agarwal, A K; Kapoor, K K; Mehrotra, H KItem Abnormal haemoglobins in the Pakistani Armed Forces personnel.(1976-06-01) Sharma, N P; Gupta, S C; Atal, P R; Mehrotra, T N; Agarwal, A K; Kapoor, K KItem Acute aortic regurgitation (report of four cases).(1981-01-01) Agarwal, A K; Prakash, S K; Yadav, P; Bhargava, M; Gupta, H LItem Acute neurobehavioural toxicity of phosphamindon and its drug-induced alteration.(1990-04-01) Agarwal, A K; Sankaranarayanan, A; Sharma, P LPhosphamidon, a systemic organophosphate insecticide, (1.4 mg/kg - dose 1/4th of LD50 given ip), produced several autonomic, neurological and behavioral effects in mice with peak effects being at 15 min. Similar dose in rats also abolished conditioned avoidance response. Pre-treatment with atropine, iproniazid, alpha-methyl-p-tyrosine, p-chlorophenylalanine or thiosemicarbazide reduce many of these effects. This suggests that phosphamidon toxicity involves the central cholinergic, adrenergic, serotonergic and GABAergic systems in addition to peripheral cholinergic effects.Item Acute renal failure and jaundice in severe falciparum malaria.(1994-08-01) Agarwal, A K; Chandra, S; Wadhwa, S; Sangla, K SItem Acute sulphone poisoning.(1981-03-01) Khan, M A; Singh, S D; Agarwal, A KItem Advances in treatment of neurocysticercosis.(1994-01-01) Agarwal, A K; Dudeja, R K; Chandra, SItem Adverse effects of hormone replacement therapy.(2001-12-09) Tripathi, B K; Gupta, B; Agarwal, A KItem Aetiology and clinical profile of osteomalacia in adolescent girls in northern India.(2003-05-22) Rajeswari, J; Balasubramanian, K; Bhatia, V; Sharma, V P; Agarwal, A KBACKGROUND: The adolescent age group is particularly prone to nutritional rickets/osteomalacia due to an increased demand for nutrients, especially calcium and vitamin D. Osteomalacia presents with non-specific signs and symptoms because of which diagnosis may be delayed. Vitamin D deficiency is unexpected in India, which is a tropical country with abundant sunshine. METHODS: We prospectively studied the clinical presentation, aetiology and social factors contributing to adolescent rickets/ osteomalacia in our region. RESULTS: We saw 21 symptomatic adolescents with osteomalacia during the study period (November 2000-July 2002). All were girls. Only 1 practised purda and 4 belonged to a low socioeconomic class. The mean (SD) duration of illness before correct diagnosis was 2.8 (2.1) years. Bone pains and muscular weakness were universally present. Non-specific complaints (especially limb pains being mistaken for joint involvement) led to a delay in diagnosis with consequent morbidity. All but 1 patient had low serum 25-hydroxyvitamin D levels (<10 ng/ml), with the mean (SD) being 4.9 (2.7) ng/ml. Their mean dietary calcium intake was low 1265 (199) mg/day, range 40-810 mg/day]. Restricted outdoor activities (n = 19) and the traditional dress code (n = 21) were contributory factors, as they led to poor exposure to sunshine. CONCLUSIONS: Nutritional osteomalacia among adolescents is a poorly recognized entity. Even in non-purda practising communities in the tropics, poor exposure to sunshine due to social factors, compounded by low dietary calcium intake, can lead to osteomalacia in adolescents.Item Allergic bronchopulmonary aspergillosis with aspergilloma mimicking fibrocavitary pulmonary tuberculosis.(1996-06-01) Agarwal, A K; Bhagat, R; Panchal, N; Shah, AA 47-year-old male, who presented with chronic fibrocavitary pulmonary disease, had received three courses of antituberculous therapy over a period of 17 years without relief. Four years prior to referred he had developed hemoptysis and rhinitis. Evaluation of the patient led to the diagnosis of allergic bronchopulmonary aspergillosis with coexistent aspergilloma, a rather uncommon association. Both his pulmonary and nasal symptoms showed a remarkable response to treatment with oral prednisolone. However, the possibility of concomitant allergic Aspergillus sinusitis remained open as the patient refused to undergo any invasive procedure.Item Artemisinin derivatives for falciparum malaria.(1999-02-22) Tripathi, B K; Agarwal, A K; Gupta, BItem Benign tumours of the breast with special reference to cellular enzymatic activity.(1976-09-01) Srivastava, V K; Wahi, K; Mittal, V P; Agarwal, A K; Rajvanshi, V SItem Bilateral miliary pattern in sarcoidosis.(1997-10-09) Chugh, I M; Agarwal, A K; Arora, V K; Shah, AItem Bradycardia dependant left bundle branch block.(1980-04-01) Singhal, S S; Agarwal, A KItem Brief psychotherapy in children. Some culture specific aspects.(1973-12-01) Agarwal, A KItem Carotid intimomedial thickness in type 2 diabetic patients and its correlation with coronary risk factors.(2008-08-05) Agarwal, A K; Gupta, P K; Singla, S; Garg, U; Prasad, A; Yadav, RAIMS: To compare the carotid intimal-medial thickness in type 2 diabetics with and without coronary artery disease (CAD), and to correlate the intimal-medial thickness (IMT) with known coronary risk factors. METHODS: One hundred and eleven patients of type 2 diabetes were recruited for the study. History and physical examination were recorded. Laboratory investigations included fasting and 2-hour post-prandial blood sugar, blood urea, serum creatinine, lipid profile, glycated haemoglobin, and microalbuminuria. Ultrasonographic scanning of the carotid arteries was performed to measure the carotid IMT. For identification of cases of silent ischaemia, treadmill test (TMT) was performed. RESULTS: The study group was divided into a non-CAD group (n=40), and a CAD group (n=71). The mean carotid IMT of the group as a whole, was 0.840 +/- 0.2 mm. The mean carotid IMT was significantly higher (p<0.0001) in type 2 diabetics with CAD (both overt and silent) than in those without CAD. In diabetics with CAD, the systolic blood pressure, diastolic blood pressure and triglycerides were found to be predictors of high mean carotid IMT. On subgroup analysis of the cases with silent ischaemia, the variables affecting carotid IMT were serum creatinine, total cholesterol, microalbuminuria/proteinuria, serum triglyceride levels, and diastolic blood pressure. CONCLUSION: A high carotid IMT is a surrogate and reliable marker of higher risk of CAD amongst type 2 diabetic patients, even in those without overt CAD. The study underlines the utility of carotid IMT as a simple, non-invasive, safe, and cheap screening test for the assessment of risk/prognosis of CAD in type 2 diabetics. We have also demonstrated the usefulness of measuring IMT, as a means to detect silent CAD among type 2 diabetics.Item Cephalosporins.(1994-04-01) Agarwal, A KItem Characterisation of adrenoceptors mediating leucocytosis in rabbits.(1985-06-01) Srivastava, V K; Agarwal, A K; Srivastava, R K; Jaju, B PItem Characterization of ribosomal RNA & proteins from Rhizobium cells, bacteroids & Phaseolus aureus roots.(1976-09-01) Agarwal, A K; Mehta, S LItem Characterization of soluble and structural proteins of Rhizobium cells and bacteroids from root nodules.(1976-06-01) Agarwal, A K; Mehta, S L