Toxoplasmosis in Humans and Animals in Ghana (1962 – 2020): A Review

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dc.contributor.authorAmissah-Reynolds, Papa Kofien_US
dc.date.accessioned2020-10-16T08:44:48Z
dc.date.available2020-10-16T08:44:48Z
dc.date.issued2020-09
dc.description.abstractToxoplasmosis is a worldwide zoonosis caused by the ubiquitous, Apicomplexan parasite, Toxoplasmagondii. This disease remains a significant aetiologic factor in pregnant women and HIV patients. In Sub-Saharan African countries like Ghana, the low antiviral therapy coverage exacerbates the risk of HIV-related mortality resulting from concurrent infections like toxoplasmosis. This paper reviews published data on toxoplasmosis in both humans and animals in Ghana. Serological surveys in humans indicate high prevalence of toxoplasmosis (up to 92.5%) in a cross-section of Ghanaians, including pregnant women and their neonates, blood donors, as well as HIV and eye patients. Limited data from epidemiological surveys also show Toxoplasmainfections in four food animals, with the prevalence ranging from 7.5% to as high as 64%. Molecular analyses in animals have also revealed three novel genotypes, TgCkGh1, TgCkGh2 and TgCtGh1. There are, however, no reports in other food animals like dogs, cattle and grasscutters in Ghana. The role of environmental matrices in the epidemiology of the disease also needs to be investigated. There is paucity of data in the Northern part of Ghana, with most reports concentrated on Southern Ghana, thus necessitating nationwide surveysunder a ‘One-Health’ concept to inform management of the disease. Policies which mandate screening of expectant mothers and blood donors are recommended to limit disease transmission in Ghana.ReviewArticle.en_US
dc.identifier.affiliationsDepartment of Science Education, Faculty of Science and Environment Education,College of Agriculture Education, Asante-Mampong, University of Education, Winneba, Ghanaen_US
dc.identifier.citationAmissah-Reynolds Papa Kofi. Toxoplasmosis in Humans and Animals in Ghana (1962 – 2020): A Review. International Journal of TROPICAL DISEASE & Health. 2020 Sep; 41(14): 20-31en_US
dc.identifier.issn2278–1005
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/209627
dc.languageenen_US
dc.publisherSCIENCEDOMAIN internationalen_US
dc.relation.issuenumber14en_US
dc.relation.volume41en_US
dc.source.urihttps://dx.doi.org//10..9734/ijtdh/2020/v41i1330350en_US
dc.subjectEpidemiologyen_US
dc.subjectseroprevalenceen_US
dc.subjectGhanaen_US
dc.subjecthumansen_US
dc.subjectanimalsen_US
dc.subjectToxoplasma gondiien_US
dc.titleToxoplasmosis in Humans and Animals in Ghana (1962 – 2020): A Reviewen_US
dc.typeJournal Articleen_US
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